» Sign in / Register

Jena Bioscience News Blog

RSS

Feb 21, 2019

Fission Impossible: Non-hydrolyzable nucleotide analogs

Nucleotides & Nucleosides Non-Hydrolyzable Nucleotides

To study:

  • protein-protein interactions
  • structure and dynamics of protein-nucleotide-complexes
  • NTPase kinetics
Learn more!

read more

Jan 18, 2019

Shining a Spotlight on Nucleotide-Protein Interactions

Nucleotides & Nucleosides

Fluorescent nucleotide conjugates are analytical tools with exceptional versatility. By covering a plethora of fluorescence-based techniques they are applied as drug screening probes, in cytoskeletal imaging and in nucleotide-protein interaction studies. Learn more!

read more

Nov 30, 2018

LNA-NTPs

Nucleotides & Nucleosides

LNA-ATP, LNA-GTP, LNA-CTP and LNA-UTP for DNA and RNA incorporation studies are now available.

Oct 30, 2018

Nucleotide Chemotherapeutics – A Success Story Goes On!

Nucleotides & Nucleosides Tenofovir

Antiviral and Cytostatic Nucleotide Analogs to

  • Study pharmacology
  • Elucidate metabolic pathways
  • Improve the potency
Check out our range of nucleotide chemotherapeutic derivatives!

read more

Sep 24, 2018

4-Seleno-dTTP: NGS-based mapping of m6A-modified RNA sites

Nucleotides & Nucleosides How it works

4SedTTP permits the identification of methylated adenosines

  • at single nucleotide resolution
  • without antibodies
  • in an NGS-based approach
How it works:

read more

Sep 12, 2018

4-Selenothymidine-5'-triphosphate

Nucleotides & Nucleosides

4SedTTP for precise antibody-independent m6A identification is now available.

Aug 31, 2018

Nucleotides & qPCR: Easy online Search

General Nucleotides & Nucleosides Click Chemistry Molecular Biology Probes & Epigenetics Nucleotides & qPCR: Easy online Search

Looking for nucleotides based on their structure or for a specific application?
Want to find the most suitable qPCR mix for your assay?

read more

Jul 03, 2018

dNTP Guide – High Performance Nucleotides

Nucleotides & Nucleosides Molecular Biology

Because nucleotides don't get better than this. Click here!

Jun 21, 2018

New in Click Chemistry: 2'-Azido-2'-dATP

Nucleotides & Nucleosides Click Chemistry

We added 2'-Azido-2'-dATP to our Click Chemistry section. For more details please click here.

Jun 04, 2018

Di-Adenosine Polyphosphates: Bacterial Signaling Molecules

Nucleotides & Nucleosides

The mode of ApnA function in bacterial signaling is awaiting its elucidation. Click to see what our compounds can contribute!

read more

May 16, 2018

Why are you still using radioactively labeled Probes?

Probes & Epigenetics Nucleotides & Nucleosides Discover the good news!

If you’re running experiments like Northern and Southern blots, or EMSA, you’re probably using radioactively labeled probes, right?
There’s good news and bad news.
The bad news is that radioactively labeled probes have a limited half-life and require special laboratory equipment...
DISCOVER THE GOOD NEWS!

read more

May 09, 2018

New: 3' End Oligonucleotide Labeling Kits

Probes & Epigenetics Nucleotides & Nucleosides

3' End Oligonucleotide Labeling Kits for preparation of Biotin- or Digoxigenin-labeled ssDNA/oligonucleotide probes are now available.

May 08, 2018

High Concentration Biotin-11-UTP

Nucleotides & Nucleosides

We now offer 75 mM Biotin-11-UTP in addition to our standard 10 mM Biotin-11-UTP solution.

Apr 18, 2018

FSBA and FSBG: Universal Traps for Triphosphate-Cleaving Enzymes

Nucleotides & Nucleosides

Probing ATPases, G-Proteins, Kinases, and Polymerases with Sulfonyl Fluoride Nucleosides – See how it can help your research!

read more

Apr 12, 2018

Biotin-14-dATP and -dCTP for Hi-C Experiments

Nucleotides & Nucleosides

Hi-C experiments allow analyses of spatial genome organization. Adjacent genome regions are tagged by enzymatic biotinylation using Biotin-14-dATP or Biotin-14-dCTP and subsequently identified by (next generation) sequencing.

read more

Mar 01, 2018

Catch and Release of Diols with Boronic Acid Agarose

Nucleotides & Nucleosides Proteins

The immobilization of boronic acids on solid support offers a versatile approach to isolate a diverse set of biomolecular diols from complex mixtures. Learn more...

Feb 27, 2018

c-di-AMP – The Messenger You Can't Ignore

Nucleotides & Nucleosides

Research on bacterial second messengers has recently experienced tremendous progress, and cyclic di-AMP (c-di-AMP) is one of the rising stars.

read more

Feb 16, 2018

New DNA/RNA labeling nucleotides

Nucleotides & Nucleosides Probes & Epigenetics

We now offer Biotin-14-dCTP, Biotin-11-ATP and dUTP-XX-ATTO-425 for enzymatic DNA/RNA labeling.
Nucleotide Selector for DNA/RNA Labeling

Jan 16, 2018

Now available: c-di-AMP

Nucleotides & Nucleosides

cyclic-di-AMP - The pleiotropic bacterial second messenger now adds to our cyclic-di-Nucleotide portfolio.

Dec 06, 2017

Now available: FSBG

Nucleotides & Nucleosides

FSBG (5'-O-(4-fluorosulfonylbenzoyl)-guanosine) – a Sulfonyl-Fluoride probe for affinity labeling of Guanine-Nucleotide binding proteins – is now available.

Nov 15, 2017

New online tool: Nucleotide Selector

Nucleotides & Nucleosides Probes & Epigenetics

Select a suitable nucleotide substrate for enzymatic DNA/RNA Labeling with our Nucleotide Selector for DNA/RNA Labeling.

Nov 10, 2017

New Azide-modified (d)UTPs

Nucleotides & Nucleosides Click Chemistry

We now offer 5-Azidomethyl-dUTP and 5-Azidomethyl-UTP.

Nov 02, 2017

Click Chemistry Talk: PDF now available

Click Chemistry Nucleotides & Nucleosides

On October 24, Dr. André Krause gave a talk at HKI Jena titled "Click Chemistry – Expanding the Scope of Nucleic Acid Labeling". Download the slides of the talk now!

Sep 28, 2017

dUTP-XX-AF488

Nucleotides & Nucleosides Probes & Epigenetics

In addition to dUTP-XX-ATTO-488, we now offer another photostable Fluorescein-12-dUTP alternative with excellent enzymatic substrate properties: dUTP-XX-AF488

Sep 05, 2017

cyclic di-GMP

Nucleotides & Nucleosides

Cyclic di-GMP is now available for signal transduction studies.

Jun 13, 2017

SCNAC 2017 – Conference Pictures

General Nucleotides & Nucleosides

We just returned from the wonderful SCNAC meeting, held in Český Krumlov/CZ. See our pictures and videos here!

May 23, 2017

Efficient Cy3 and Cy5 RNA Labeling

Probes & Epigenetics Nucleotides & Nucleosides

We now offer linker-optimized Cy3- and Cy5-modified UTPs (UTP-X-Cy3 (= Cy3-17-UTP) and UTP-X-Cy5 (= Cy5-17-UTP)) for in vitro transcription based labeling.

Apr 05, 2017

New: 19F-NMR probes

Nucleotides & Nucleosides

Our new nucleotides can be used as 19F-NMR probes.

Mar 24, 2017

Improved Cy3 and Cy5 DNA labeling efficiency

Probes & Epigenetics Nucleotides & Nucleosides

Linker-optimized Cy3- and Cy5-modified dUTPs (dUTP-XX-Cy3 and
dUTP-XX-Cy5) are now available that show higher labeling efficiencies at similar dTTP substitution rates.

Jan 31, 2017

Price cut on 5-hmdCTP and 5-mdCTP

Nucleotides & Nucleosides

Check out our significantly reduced prices for 5-hydroxymethyl-dCTP (5-hmdCTP) and 5-methyl-dCTP (5-mdCTP).

Jan 06, 2017

Biotin-14-dATP

Nucleotides & Nucleosides

Our portfolio of biotinylated nucleotides for enzymatic DNA labeling has been extended by Biotin-14-dATP.

Nov 04, 2016

GppNHp (GMPPNP) - Trisodium salt

Nucleotides & Nucleosides

GppNHp now also available as trisodium salt.

Sep 21, 2016

5'-RNA labeling

Nucleotides & Nucleosides

Biotin-AMP is now available for 5'-RNA labeling by in vitro transcription.

Sep 16, 2016

m-Aminophenylboronic acid-Agarose

Proteins Nucleotides & Nucleosides

Now available! Immobilized m-Aminophenylboronic acid, our affinity resin of choice for the enrichment of 1,2-cis-diols such as ribonucleotides, cofactors and carbohydrates. Due to its high exclusion limit also suitable for the purification of RNA and glycosylated proteins.