Dec 08, 2020
RNA synthesis kits with a T7 RNA polymerase triple mutant are now available for efficient 2'F-modified Aptamers preparation:
2'F-dUTP-based, 2'F-dCTP-based, 2'F-dGTP-based, 2'F-dATP-based
Nov 19, 2020
5’-capping and internal epigenetic base modifications significantly increase translation efficiency while reducing immunogenicity of synthetic (viral) mRNA. Read more...
Nov 03, 2020
Double-stranded RNA (dsRNA) is a key molecule in RNA interference (RNAi)-mediated gene silencing at the mRNA level. Large amounts of dsRNA can be efficiently synthesized via in vitro transcription.
Oct 06, 2020
Structural investigations of RNA require a homogenous RNA preparation. Learn how to reduce in vitro transcription-caused 5' heterogeneity!
Sep 09, 2020
Explore the advantages of using 4-Thio-uridine containing products to identify RNA-protein interactions both in cells and in vitro!
Jun 16, 2020
HighYield T7 RNAi Kit is now available for the production of dsRNA >200 bp that can subsequently be used for RNA interference (RNAi) applications.
Jun 11, 2020
Poly (A) carrier RNA facilitates quantitative purification of low RNA amounts. Read more...
Jun 09, 2020
T7 RNA Polymerase (HC) is now available for set-up and optimization of individual high yield in vitro transcription reactions.
Jun 06, 2020
We now offer Poly(A) carrier RNA for quantitative purification of RNA and DNA.
Apr 08, 2020
Efficient preparation of AF (Alexa Fluor®)-Dye labeled RNA is now easily achievable via in vitro transcription. Read more...
Apr 03, 2020
SCICONS Anti-dsRNA monoclonal antibodies are efficient tools for the detection of dsRNA both in cell culture and FFPE samples. Read more...
Mar 26, 2020
We now offer SCICONS Anti-dsRNA monoclonal antibodies J2, K1 and K2.
Mar 20, 2020
Efficient AF(Alexa Fluor®)-dye RNA labeling is now feasible with our HighYield T7 AF488-, HighYield T7 AF555-, HighYield T7 AF594- and HighYield T7 AF647-RNA Labeling Kits.
Mar 04, 2020
We now offer AF 488 (Alexa Fluor® 488)-, AF546 (Alexa Fluor® 546)- and AF594 (Alexa Fluor® 594)-labeled tyramide to increase detection sensitivity of horseradish peroxidase (HRP)-based assays.
Feb 24, 2020
We now offer a HighYield RNA Synthesis Kit based on a modified T7 RNA Polymerase that has been associated with decreased abortive transcription, increased transcript 5' homogeneity and increased 5' incorporation efficiency of GTP analogs.
Feb 06, 2020
5’-capping and epigenetic nucleotide modifications are critical for efficient translation and reduced immunogenicity of synthetic mRNA. The classic combination of modifications consists of ARCA, 5-methylcytidine and pseudouridine. Promising extensions of the mRNA modification toolbox are available.
Jan 24, 2020
We now offer ATTO680 NT Labeling kit for the preparation of ATTO680-labeled DNA probes via nick translation.
Nov 05, 2019
Current near-IR fluorescent RNA probes use dye-labeled nucleotides with only moderate sensitivity. Use copper-free CLICK labeling for increased sensitivity. Learn more here!
Oct 01, 2019
CRISPR/Cas systems are the most flexible and efficient site-directed gene targeting tools currently available. Learn more!
Sep 30, 2019
We now offer a convenient and efficient HighYield T7 sgRNA Synthesis Kit (SpCas9) for cloning-free preparation of SpCas9-specific sgRNA. Individual (s)gRNA-encoding T7 DNA templates (e.g with a different Cas9 scaffold or for different Cas endonucleases) can efficiently be in vitro transcribed with the HighYield T7 RNA Synthesis Kit.
Sep 11, 2019
We now offer RNA-modifying enzymes: T4 RNA Ligase 1, Yeast Poly(A) Polymerase, E. coli Poly(A) Polymerase.
Aug 19, 2019
We now offer HighYield kits for synthesis of ARCA-capped and/or 5-methylcytosine & pseudouridine-modified (m)RNA.
Jun 25, 2019
HighYield T7 RNA Labeling Kits for preparation of Digoxigenin, Biotin and fluorescent RNA probes are now available. The single nucleotide format offers maximum optimization flexibility.
Jun 07, 2019
Now available! Our HighYield T7 RNA Synthesis Kit is designed for the efficient production of unmodified and modified RNA.
Jun 04, 2019
Numerous non-coding RNAs such lncRNAs, snRNAs, circRNAs or miRNAs are constantly identified hence their functional characterization is of great importance.
Learn how current aptamer-based RNA imaging and analysis strategies contribute to characterization of a specific RNA.
Mar 07, 2019
Looking for products to support your RNA research? Then have a look here!
Feb 18, 2019
Looking for products to support your RNA research? Have a look at our new RNA Technologies section.
Our product portfolio will constantly be extended. Want to stay updated?
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