» Sign in / Register

Jena Bioscience News Blog

RSS

Dec 08, 2020

Efficient enzymatic preparation of 2'F-modified Aptamers

RNA Technologies

RNA synthesis kits with a T7 RNA polymerase triple mutant are now available for efficient 2'F-modified Aptamers preparation:
2'F-dUTP-based, 2'F-dCTP-based, 2'F-dGTP-based, 2'F-dATP-based

Nov 19, 2020

Increase synthetic (viral) mRNA functionality with epigenetic modifications

RNA Technologies Read more...

5’-capping and internal epigenetic base modifications significantly increase translation efficiency while reducing immunogenicity of synthetic (viral) mRNA. Read more...

read more

Nov 03, 2020

Efficient dsRNA synthesis for RNAi applications

RNA Technologies Read more...

Double-stranded RNA (dsRNA) is a key molecule in RNA interference (RNAi)-mediated gene silencing at the mRNA level. Large amounts of dsRNA can be efficiently synthesized via in vitro transcription.

read more

Oct 06, 2020

Increase 5' homogeneity of in vitro transcribed RNA

RNA Technologies Read more...

Structural investigations of RNA require a homogenous RNA preparation. Learn how to reduce in vitro transcription-caused 5' heterogeneity!

read more

Sep 09, 2020

RNA-Protein Photocrosslinking: Site- and sequence-specific Tracking

Nucleotides & Nucleosides RNA Technologies Click here and see how it works

Explore the advantages of using 4-Thio-uridine containing products to identify RNA-protein interactions both in cells and in vitro!

read more

Jun 16, 2020

New: HighYield T7 RNAi Kit

RNA Technologies

HighYield T7 RNAi Kit is now available for the production of dsRNA >200 bp that can subsequently be used for RNA interference (RNAi) applications.

Jun 11, 2020

Poly (A) carrier RNA: Improved viral RNA recovery

RNA Technologies Learn more...

Poly (A) carrier RNA facilitates quantitative purification of low RNA amounts. Read more...

read more

Jun 09, 2020

New: Highly concentrated T7 RNA Polymerase version

RNA Technologies

T7 RNA Polymerase (HC) is now available for set-up and optimization of individual high yield in vitro transcription reactions.

Jun 06, 2020

Now available: Poly(A) carrier RNA

RNA Technologies Molecular Biology

We now offer Poly(A) carrier RNA for quantitative purification of RNA and DNA.

Apr 08, 2020

Efficient RNA Labeling with AF (Alexa Fluor®)-Dyes

RNA Technologies Read more...

Efficient preparation of AF (Alexa Fluor®)-Dye labeled RNA is now easily achievable via in vitro transcription. Read more...

read more

Apr 03, 2020

The gold standard in viral dsRNA detection: Monoclonal J2, K1 & K2 antibodies

RNA Technologies Read more...

SCICONS Anti-dsRNA monoclonal antibodies are efficient tools for the detection of dsRNA both in cell culture and FFPE samples. Read more...

read more

Mar 26, 2020

Monoclonal antibodies for (viral) dsRNA detection

RNA Technologies

We now offer SCICONS Anti-dsRNA monoclonal antibodies J2, K1 and K2.

Mar 20, 2020

AF(Alexa Fluor®)-dye RNA Labeling Kits

RNA Technologies

Efficient AF(Alexa Fluor®)-dye RNA labeling is now feasible with our HighYield T7 AF488-, HighYield T7 AF555-, HighYield T7 AF594- and HighYield T7 AF647-RNA Labeling Kits.

Mar 04, 2020

Increased detection sensitivity with fluorescent tyramides

RNA Technologies

We now offer AF 488 (Alexa Fluor® 488)-, AF546 (Alexa Fluor® 546)- and AF594 (Alexa Fluor® 594)-labeled tyramide to increase detection sensitivity of horseradish peroxidase (HRP)-based assays.

Feb 24, 2020

New: HighYield T7 P&L RNA Synthesis Kit

RNA Technologies

We now offer a HighYield RNA Synthesis Kit based on a modified T7 RNA Polymerase that has been associated with decreased abortive transcription, increased transcript 5' homogeneity and increased 5' incorporation efficiency of GTP analogs.

Feb 06, 2020

Modified mRNA synthesis beyond the classics

RNA Technologies Read more...

5’-capping and epigenetic nucleotide modifications are critical for efficient translation and reduced immunogenicity of synthetic mRNA. The classic combination of modifications consists of ARCA, 5-methylcytidine and pseudouridine. Promising extensions of the mRNA modification toolbox are available.

read more

Jan 24, 2020

IR dye - labeled DNA Probes

RNA Technologies Probes & Epigenetics

We now offer ATTO680 NT Labeling kit for the preparation of ATTO680-labeled DNA probes via nick translation.

Nov 05, 2019

Northern Blots: 0.05 fmol detection limit with near-IR RNA Probes

RNA Technologies Learn more...

Current near-IR fluorescent RNA probes use dye-labeled nucleotides with only moderate sensitivity. Use copper-free CLICK labeling for increased sensitivity. Learn more here!

read more

Oct 01, 2019

CRISPR/Cas: RNA-guided gene targeting

RNA Technologies CRISPR/Cas tools

CRISPR/Cas systems are the most flexible and efficient site-directed gene targeting tools currently available. Learn more!

read more

Sep 30, 2019

SpCas9-specific sgRNA Synthesis

RNA Technologies

We now offer a convenient and efficient HighYield T7 sgRNA Synthesis Kit (SpCas9) for cloning-free preparation of SpCas9-specific sgRNA. Individual (s)gRNA-encoding T7 DNA templates (e.g with a different Cas9 scaffold or for different Cas endonucleases) can efficiently be in vitro transcribed with the HighYield T7 RNA Synthesis Kit.

Aug 19, 2019

Interested in ARCA-capped and internally modified RNA?

RNA Technologies

We now offer HighYield kits for synthesis of ARCA-capped and/or 5-methylcytosine & pseudouridine-modified (m)RNA.

Jun 25, 2019

New HighYield T7 RNA Labeling Kits

RNA Technologies

HighYield T7 RNA Labeling Kits for preparation of Digoxigenin, Biotin and fluorescent RNA probes are now available. The single nucleotide format offers maximum optimization flexibility.

Jun 07, 2019

HighYield T7 RNA Synthesis Kit

RNA Technologies

Now available! Our HighYield T7 RNA Synthesis Kit is designed for the efficient production of unmodified and modified RNA.

Jun 04, 2019

Why image RNA?

RNA Technologies Learn more...

Numerous non-coding RNAs such lncRNAs, snRNAs, circRNAs or miRNAs are constantly identified hence their functional characterization is of great importance.
Learn how current aptamer-based RNA imaging and analysis strategies contribute to characterization of a specific RNA.

read more

Mar 07, 2019

New Section: RNA Technologies

RNA Technologies Learn more...

Looking for products to support your RNA research? Then have a look here!

read more

Feb 18, 2019

New Section: RNA Technologies

RNA Technologies

Looking for products to support your RNA research? Have a look at our new RNA Technologies section.
Our product portfolio will constantly be extended. Want to stay updated?
Sign up for our RNATech newsletter or contact us at rnatech@jenabioscience.com!