Extended CLICK nucleotide portfolio
Both 5-Ethynyl-dCTP and 5'-Azidohexyl-pApG are now available as catalog products.

Featured Article - June 2026: Molecular mechanisms of autoinflammation
"NK cell dysfunction and interferon-γ production underlie autoinflammation in mevalonate kinase deficiency." by Munoz et al. (Immunity, Jun 09, 2026) is our featured scientific article for June. Read our summary!

Advancing EBV Research: Harnessing LEXSY technology for BGLF4 protein kinase expression and discovery
LEXSY technology offers an efficient and scalable platform for expressing viral replication proteins, facilitating advanced research and vaccine development. Check out our references!

When to Choose What? RNA Detection Strategies
Emerging viral outbreaks demand fast, reliable RNA detection. Discover flexible solutions for RNA purification, classical RT-qPCR, direct amplification and ultrafast RT-LAMP analysis. Explore our RNA detection options here!

Optimized HighYield T7 RNA Labeling Kit configuration for enhanced flexibility
Our HighYield T7 RNA Labeling Kits have been extended with an additional reaction buffer for enhanced assay set-up flexibility. Read more...

Upcoming Price Adjustment for Quantifoil Grids
We would like to inform our customers in advance about an upcoming price adjustment for Quantifoil grids. Although our purchasing costs for Quantifoil grids increased several months ago, we have continued to absorb these additional costs to keep our prices stable for our customers. As of July 1, we will however need to adjust our prices accordingly. All orders received by June 30 will still benefit from the current prices. Thank you for your understanding!

Wir stellen ein / We are hiring
Abteilungsleiter IT (m/w/d) und IT-Administrator/Systembetreuer (m/w/d) – Details finden Sie in der Rubrik Careers.

Introducing our new MeatDetect qPCR Kit – Chicken & Turkey
Discover our newly released Chicken & Turkey MeatDetect qPCR Kit – a fast and sensitive multiplex assay designed for food and feed analysis. Detect chicken and turkey DNA in raw, cooked and processed samples reliably and with minimal hands-on time. Learn more...

Featured Article - May 2026: Insights into Bacterial Virulence
"Reprogramming of bacterial virulence by lysine acetylation." by Schmöker et al. (Nature Communications, Apr 27, 2026) is our featured scientific article for May. Learn more here!

Significant price reduction for TEW
Anderson−Evans polyoxotungstate (TEW) is a universal additive for protein crystallization, proven to promote crystallization while improving crystal quality and providing a valuable anomalous signal for phasing. TEW is now available at a significantly reduced price!

Meet us – The Molecular Biology Unit
Molecular Biology at Jena Bioscience is defined by experience, reliable expertise and close collaboration with other JBS departments. Get more insights here!

Featured Article - April 2026
"A single viral enzyme drives tRNA-dependent DNA hypermodification." by Silva et al. (Nature Communications, Apr 03, 2026) is our featured scientific article for April. Read more here!

High sensitivity & low background detection: Digoxigenin-labeled DNA & RNA probes
Explore our toolbox for enzymatic Digoxigenin labeling of DNA and RNA probes. Read more...

JBScreen Wizard – Smart Screening Solutions for Crystallization Success
Streamline your crystallization workflow with JBScreen Wizard. Systematically designed screening kits combine well-established conditions with innovative formulations to efficiently explore crystallization space - helping you identify initial hits faster and optimize them with confidence.

Featured Article - March 2026
"Allosteric targeting with antiviral nucleotide analogs allows fine tuning of SAMHD1 dNTPase activity." by Dirks et al. (Journal of Biological Chemistry, Jan 29, 2026) is our featured scientific article for March. Read the full story!

Turning citations into credibility: how Jena Bioscience strengthens digital trust with Bioz
We have been partnering with Bioz for many years to display up-to-date product citations in scientific literature on our website. Bioz now features Jena Bioscience in their latest success story - read it here!

Rapid RNA detection – now more accessible than ever
Looking for a faster, easier way to detect RNA? Our Saphir RT-LAMP Kit delivers results in just 5-10 minutes – no thermal cycler needed. Easy to use, highly reliable, and perfect for point-of-care diagnostics, animal health and food safety testing, and many more.

Now available: DIG-11-dCTP
We extended our portfolio of Digoxigenin-modified nucleotides with DIG-11-dCTP.

Choose reagents with confidence – product citations powered by Bioz
In science, access to publications is crucial for selecting products for a specific application. Bioz’ technology provides real-time access to the latest product citations in scientific literature to help you establish your assay of interest. Learn how it works!

5’-Azido-puromycin: Copper-free CLICK labeling of newly synthesized proteins
5’-Azido-puromycin allows visualization of newly synthesized proteins via copper-free CLICK labeling. Read more...

Featured Article - February 2026
"AquIRE reveals the mechanisms of clinically induced RNA damage and the conversation and dynamics of glycoRNAs." by Zhang et al. (Nucleic Acid Research, Feb 27, 2026) is our featured scientific article for February. Read the full story!

Wir stellen ein / We are hiring
Technischer Assistent (m/w/d) - Enzymatische Herstellung modifizierter Nukleotide – Details entnehmen Sie bitte dieser Seite.

New cap analog m7GP3N6-AH-BioA
We extended our portfolio of cap analogs with a biotinylated version: m7GpppA-N6-aminohexyl-Biotin (m7GP3N6-AH-BioA).

Extended CLICK nucleotide portfolio:
2'-Azido-2'-dGTP and 5-Ethynyl-CTP are now available as catalog products. Check out our complete portfolio of CLICK-functionalized nucleotides as well: Azide-functionalized nucleotides Alkyne-functionalized nucleotides DBCO-functionalized nucleotides

Molecular Biology Products Tailored to Your Needs – Bulk & OEM Solutions by Jena Bioscience!
Are you looking for reliable qPCR mixes, polymerases or nucleotides for large-scale applications? At Jena Bioscience, we support research labs and biotech companies with flexible bulk and OEM solutions – designed to scale with your needs.

Nourseothricin (clonNAT) – Flexible and reliable antibiotic selection at attractive prices
Need a selection antibiotic for your organism? Nourseothricin can be used for selection of over 100 different species from all kingdoms of life – at affordable costs!

Featured Article: Ligand specific activation trajectories dictate GPCR signaling in cells
"Ligand specific activation trajectories dictate GPCR signaling in cells" - by Thomas et al. (Nature, Jan 14, 2026) is our featured scientific article for January. Read the full story!

DNA Synthesis Monitoring in Zebrafish
Discover a stepwise protocol for 5-EdU incorporation and subsequent DNA synthesis detection via Copper-catalyzed Click Chemistry in Zebrafish.

Reversibly 3'-O-blocked (d)NTPs: Building blocks for controlled, stepwise DNA & RNA synthesis
Explore our toolbox of reversible 3’-O-blocked nucleotides beyond their application in short-read sequencing-by synthesis-methods (SBS).

Season’s Greetings from Jena Bioscience
As the year comes to an end, we want to say thank you – thank you for your trust in our products and for the inspiring collaboration we shared with you throughout the past twelve months.

Last shipping days in 2025
Please note our last regular shipping days in 2025: Tue, Dec 16: all non-European countries Wed, Dec 17: Europe Thu, Dec 18: Germany Urgent shipments will only be sent after the dates given above if customers can ensure safe receipt. Regular order processing & shipping will start again on Jan 05, 2026.

Now available: Thienoguanosine
We now offer Thienoguanosine, a fluorescent isomorphic guanosine analog, ideal for 5´-end RNA labeling via in vitro transcription.

Expanding the bacterial nucleotide second messenger vocabulary
An expanding repertoire of linear and cyclic bacterial nucleotide second messengers has been discovered during the past years. Read more...

Featured Article - November 2025
"The Panoptes system uses decoy cyclic nucleotides to defend against phage." - by Sullivan et al. (Nature, Oct 01, 2025) is our featured scientific article for November. Read the full story!

Stop Chasing Conditions - Start Finding Crystals with JCSG++
Don't leave screening to chance - screen with strategy: discover the JBScreen JCSG++ crystallization screen family! Learn more...

tCOTP: Enhancing mRNA Studies with native-like Fluorescent Labels
Discover how tCOTP is transforming RNA research and opens new possibilities for tracking mRNA delivery and function. Read more...

Tight Budget, tight Schedule? Do it directly!
From crude extract to quantitative analysis in record time? Possible with our Direct qPCR or RT-qPCR Master mixes: your solution to save time and money. Now with a new recipe and easier shipping! Read more about our All-in-one Direct Kits...

Wir bilden aus!
Für das Ausbildungsjahr 2026/2027 bieten wir interessierten Schulabgängern die Möglichkeit einer Berufsausbildung zum Biologielaboranten (m/w/d). Details findet Ihr hier!

Extended portfolio of fluorescently labeled ATPs
Our newly developed, linker-optimized fluorescent 7-Deaza-ATPs are now available as excellent substrates for T7 RNA Polymerase-mediated in vitro transcription. Read more...

New: 5-Formyl-dCTP and 5-Carboxy-dCTP
Our portfolio of epigenetically relevant pyrimidines has been complemented by 5-Formyl-dCTP and 5-Carboxy-dCTP.

Now available: ppApp and pppApp
We extended our portfolio with the alarmones Adenosine-3‘-diphosphate-5‘-diphosphate (ppApp) and Adenosine-3‘-diphosphate-5‘-triphosphate (pppApp). Check out our complete portfolio of nucleoside polyphosphates (pnNpn) as well!

Featured Article - October 2025
"Replisome passage through the cohesin ring." - by Glaser et al. (Cell, Sep 16, 2025) is our featured scientific article for October. Find out more about it!

SNP genotyping by mass spectrometry using mass-modified nucleotides
Mass-modified nucleotides allow unambiguous allele discrimination in mass spectrometry-based genotyping of single nucleotide polymorphisms (SNPs). Read more...

Crystallization of LEXSY-produced Heliorhodopsines
Producing functional, correctly folded proteins is crucial for crystallization and structure determination - LEXSY can help making these proteins.

Featured Article - September 2025
"FEN1 is critical for rapid single-strand break repair in G1 phase" - by Burdova et al. (Nucleic Acids Research, Aug 12, 2025) is our featured scientific article for September. Read why it matters!

Sequencing-by-synthesis: Fluorescent reversible 3’-O-blocked dNTPs
Fluorescent reversible 3’-O-blocked dNTPs are key components of short read sequencing technologies such as reversible termination sequencing-by-synthesis (SBS). Read more...

Quickly find what you need: Selector Tool for Cryo-EM Grids is now available!
Copper or Gold? 200, 300 or 400 Mesh size? Filter by your desired Cryo-EM Grid features and easily find exactly what you need! Read more...

Acyclo-NTPs for SNP genotyping
In addition to ddNTPs, we now offer Acyclo-NTPs (Acyclo-ATP, Acyclo-CTP, Acyclo-GTP, Acyclo-5-Br-UTP) for mass spectrometry-based SNP genotyping.

Now available: Fluorescent phosphate-modified AMPs
Check out our α-[(6-Aminohexyl)imido]-AMPs labeled with various fluorescent dyes: α-[(6-Aminohexyl)imido]-AMP-AZDye647 α-[(6-Aminohexyl)imido]-AMP-Cy5 α-[(6-Aminohexyl)imido]-AMP-AZDye555 α-[(6-Aminohexyl)imido]-AMP-Cy3 α-[(6-Aminohexyl)imido]-AMP-AZDye488

New: 2’,5’-GpAp
2’,5’-GpAp is now available that can be used as a negative control for 2’,3’-cGAMP due to its linear conformation.

Terminal fluorescently labeled deoxynucleoside hexaphosphates (dN6Ps) - Key components of long-read sequencing technologies
Terminal fluorescently labeled dN6Ps have been established as key components of long-read sequencing technologies such as single-molecule real-time sequencing (SMRT).

Now available: Cap analog m7GP32'-OmA
We extended our portfolio of RNA Cap Analogs: m7GP32'-OmA

Extended portfolio of fluorescently labeled ATPs
We now offer Fluorescently labeled 7-Propargylamino-7-Deaza-ATPs. They are excellent substrates for T7 RNA Polymerase - mediated in vitro transcription.

Better Safe Than Sorry – Detect RNase & DNase Contamination with Confidence
Hidden RNase or DNase contamination can sabotage your experiments before they even begin. Our Nuclease Detection Kit offers a quick, reliable way to ensure the safety of your buffers and reagents. When precision matters, prevention is everything. Test now & stay contamination free!

Optimize in vitro transcription reactions: A modified T7 RNA Polymerase with reduced dsRNA formation
Double-stranded RNA (dsRNA) is a critical by-product of wildtype T7 RNA Polymerase-based in vitro transcription. It needs to be minimized in final RNA preparations to reduce the risk of undesired immune responses.

Follow us beyond the bench: JBS live on social media!
We have always been passionate about what we do - now we are excited to share this passion with you.

dsRNA Antibodies: Powerful Tools for Research & Quality Control
Double-stranded RNA (dsRNA) antibodies are efficient tools for the detection of dsRNA in various samples.

Jena Bioscience – Who We Are
Ever wondered who is behind the JBS newsletter in your inbox? Here’s your chance to take a peek behind the scenes: We are real people, not just an AI assistant, providing high-quality bioscience products to researchers all around the globe, every day.

Now available: 2'-O-(2-Methoxyethyl)-NTPs
We extended our portfolio of 2'-O-methylated NTPs: 2'-O-MOE-ATP, 2'-O-MOE-GTP, 2'-O-MOE-CTP and 2'-O-MOE-UTP

Exploring the Diversity of Cyclic Di- and Trinucleotides – Key Players in Cellular Signaling
Interested in cyclic dinucleotides (CDNs) and trinucleotides (CTNs) beyond the classics such as c-diGMP or c-diAMP? Read more...

When every minute counts – choose Saphir RT-LAMP
Looking for a faster, easier way to detect RNA? Our new Saphir RT-LAMP Kit delivers results in just 5–10 minutes – no thermal cycler needed. Easy to use, highly reliable, and perfect for point-of-care diagnostics, food safety, and more.

Improve lncRNA-protein pull-down experiments with Desthiobiotinylated RNA probes
We now offer Desthiobiotin-modified NTPs and Labeling Kits for efficient enzymatic preparation of Desthiobiotinylated long non-coding RNA (lncRNA) probes. Read more...

Enhance amplification & sequencing results with 7-Deaza-dGTP and N4-Methyl-dCTP – Bulk amounts available!
7-Deaza-dGTP and N4-Methyl-dCTP are valuable nucleotide analogs used in amplification and sequencing applications of GC-rich DNA regions. Read more...

Back in stock: JBScreen Kinase HTS!
Optimize your research with our advanced kinase crystallization screen – now back in stock!

Extended portfolio of 2',3'-Cyclic Nucleotide Monophosphates (2',3'-cNMPs)
In addition to 2',3'-cCMP, we now offer 2',3'-cUMP, 2',3'-cAMP and 2',3'-cGMP as well.

Maximize Efficiency in Protein Digestion: JBS Proteinase K Solution & Powder!
Unlock precision and performance with our new Proteinase K formulations: Your reliable choice for fast protein digestion either as a ready-to-use solution or in a powdered format.

Now available: Fluorescent gamma-phosphate modified dNTPs
Check out our gamma-phosphate Cy3-labeled dNTPs: γ-(6-Aminohexyl)-dCTP-Cy3 γ-(6-Aminohexyl)-dTTP-Cy3 Contact us if you are interested in corresponding fluorescent conjugates.

Simultaneous Detection Made Easy – Experience our new qPCR MultiplexMaster!
Introducing our latest Multiplex qPCR Mix featuring a highly sensitive Hot Start Polymerase in a ready-to-use mixture with improved robustness towards qPCR inhibitors. Make it count and analyse 4 or more targets in one single run.

Black Hole Quencher™: True dark quenchers without native emission
Jena Bioscience now offers BHQ-1™-, BHQ-2™- and BHQ-10™- labeled nucleotides to quench fluorescence across different spectral ranges. Read more...

Lyophilized PCR reagents: The new gold standard for DNA & RNA analysis
Ready-to-Use Lyophilisates come as complete master mixes in a dry, room temperature stable format:Pre-aliquoted with all required reagentsStable at ambient temperatureNo cooling chain requiredMinimized risk of contamination Read more...

5-Methylcytidine modification increases self-amplifying RNA effectiveness
Katalin Karikó‘s and Drew Weissman‘s Nobel Prize-winning concept of nucleoside base modifications as basis for the development of effective mRNA vaccines has been successfully applied to self-amplifying RNA (saRNA). Read more...

Now available: Amine-functionalized nucleotide hexaphosphates (dN6P)
zeta-(6-Aminohexyl)-dA6P zeta-(6-Aminohexyl)-dG6P zeta-(6-Aminohexyl)-dC6P zeta-(6-Aminohexyl)-dT6P Interested in corresponding fluorescent conjugates? Contact us!

Extended portfolio of 3'-O-modified dNTPs
We now offer the complete set of 3'-phosphate-dNTPs such as 3'-Phosphate-dATP, 3'-Phosphate-dCTP, 3'-Phosphate-dGTP and 3'-Phosphate-dTTP.

Fluorescein-nucleotide conjugates for efficient nucleic acid labeling
We extended our portfolio of Fluorescein-labeled nucleotides for non-radioactive labeling of nucleic acids.

Extended DNP (Dinitrophenol)-labeled nucleotide portfolio
Check out our DNP (Dinitrophenol)-labeled nucleotides for efficient non-radioactive labeling of RNA and DNA: Aminoallyl-UTP-DNP Aminoallyl-dUTP-DNP Aminoallyl-CTP-DNP Aminoallyl-dCTP-DNP

Purchase VectorLabs Click Chemistry products from Jena Bioscience
The former Click Chemistry Tools & Fluoroprobes products are now available again via our cooperation partner VectorLabs. Read more...

Now available: High concentration labeled nucleotides for efficient DNA and RNA Labeling
Cy3-,Cy5- and Biotin-labeled nucleotides with increased concentration have now been added to our catalog. Check out our portfolio here!

GC-rich DNA regions: Enhance amplification & sequencing resolution
In addition to 7-Deaza-dGTP and dITP, we now offer N4-Methyl-dCTP that can be used as dCTP substitute.

LEXSY – Expression of SARS-CoV-2 spike protein and more
Recombinant protein production with the LEXSY technology yields active, correctly folded and uniformly glycosylated antigens – crucial for functional assays as well as for structure determination.

Novel fluorescent probes with improved stability and affinity for Gαi1 protein
A new generation of GTP analogs labeled with 5-FAM show improved hydrolytic stability and binding affinity for Gαi1 protein compared to commonly used MANT and BODIPY FL GTPγS. Read more...

Meet us at MedLab Middle East!
We will be at MedLab Middle East in Dubai from February 5-8. Meet us at Booth Z6.E32 in the German Pavilion!

Price Reduction for qPCR & RT-qPCR Mixes
You are looking for high-quality qPCR and RT-qPCR mixes at fair prices? Choose the best solution for your specific applications from our PCR product portfolio!

TEV Protease: Simplifying Tag Removal
Cleave your tag or fusion protein and obtain native proteins with TEV protease from Jena Bioscience! Read more...

Increase synthetic mRNA functionality with nucleoside base modifications
5’-capping and nucleoside base modifications significantly increase translation efficiency while reducing immunogenicity of synthetic mRNA. Read more...

Tight budget, tight schedule? Do it with Direct PCR!
From crude extract to quantitative analysis – our direct amplification product line can do it all. Give it a try and choose one of our Direct qPCR or RT-qPCR Master mixes to save you time and money!

Protein glycosylation: LEXSY can do
When producing proteins, proper glycosylation is often the key to success. LEXSY can recognize glycosylation sites and provide proteins with correct glycan patterns.

Efficient RNA Labeling with abberior® STAR dyes
Efficient preparation of abberior® STAR dye-labeled RNA is now easily achievable via in vitro transcription. Read more...

Now available: abberior® dye-labeled nucleotides
Select one of our catalog products UTP labeled with abberior® STAR RED dUTP labeled with abberior® STAR RED or contact us if you are interested in a different abberior® dye-nucleotide conjugate.

Real-time qPCR mixes for every application!
Direct, freeze-dried or Multiplex qPCR? Choose from Jena Bioscience’s broad selection of real-time qPCR master mixes!

Choose your ideal PCR Polymerase
Jena Bioscience offers a range of high performance DNA polymerases. We've got something for you whether you're running routine PCR, screening reactions, high throughput assays or reactions that require higher accuracy.

N1-Methylpseudouridine: Increase mRNA vaccine effectiveness
Evidence suggests that N1-Methylpseudouridine modification increases mRNA vaccine effectiveness. Read more... Research suggests that incorporation of N1-Methylpseudouridine increases mRNA vaccine effectiveness through enhanced protein expression combined with low immunogenicity. Read more...

Jena Bioscience expands range of PCR Lyophilisates!
Our new lyophilised reagents are designed for diagnostics of target DNA and RNA. Traditionally, molecular diagnostics has relied on wet reagents, requiring temperature-controlled storage and shipping. The new lyophilised PCR reagents from Jena Bioscience are shelf-stable and can save space, while still offering the same exceptional performance as our wet reagents. Check out our range of Lyophilisates:qPCR LyophilisatesRT-qPCR LyophilisatesLAMP Lyophilisates We can design individual lyophilisates according to your requirements and applications! Just contact us for more information or an individual quotation!

New: Turbo Bst Polymerase
Our new Bst Turbo Polymerase is genetically engineered for ultrafast and robust amplification. Bst Turbo is 2-3x faster than typical Bst polymerases and allows for detection of a target gene in only 5-10 minutes!

Ultrapure PCR Nucleotides
Minute impurities in dNTPs can hinder the performance of your polymerases. Many of these impurities are by-products of the chemical synthesis of dNTPs. Ultrapure dNTPs from Jena Bioscience are manufactured enzymatically, ensuring the highest performance on the market today. Individual dNTP solutions give you the flexibility to configure your PCR how you want. Our dNTP premixes are quick and easy to use with equimolar concentrations of the dNTPs.

mRNA quality control: Easy detection of dsRNA impurities
Double-stranded RNA (dsRNA) is a major impurity of therapeutic mRNA produced by in vitro transcription. Impurity levels of this transcriptional by-product need to be tightly monitored in mRNA production lots to ensure efficient mRNA expression and to reduce the risk of undesired high immunogenicity.

Hot Start Technology – avoid unspecific PCR products!
Hot Start technology developed by Jena Bioscience increases specificity and reduces false-positives. Our Hot Start Taq polymerases are inactivated at room temperature, preventing nonspecific amplification products and primer-dimers.

New: Nuclease Detection - As simple as this!
Nucleases (e.g. DNases & RNases) are enzymes facilitating the cleavage of phosphodiester bonds in nucleic acids (RNA, ss- or ds-DNA). Due to their omnipresence in the environment, they are a constant contamination risk especially to molecular biological applications such as PCR reactions.

New Distributor in India: Everon Life Sciences
We welcome Everon Life Sciences as a new distributor of Jena Bioscience's products in India! Find all contact information here.

Crystallization of LEXSY-produced Helminth proteins
Producing functional, correctly folded proteins is crucial for crystallization and structure determination. LEXSY can help making these proteins – and JBScreens can turn them into high quality crystals.

Fishing for Glyco-Proteins
Identify and isolate O-GlcNAc modifications on glyco-proteins using UDP-GalNAz! Read more...

AZDye-labeled CTPs available
We extended our portfolio of fluorescent nucleotides for in vitro transcription experiments with AZDye-labeled CTPs: CTP-PEG5-AZDye 488 CTP-PEG5-AZDye 555 CTP-PEG5-AZDye 594 CTP-PEG5-AZDye 647

Cryo-EM: Au-flats™ in 0.6/1.0 µm available
We have extended our Cryo-EM range to include the new Au-flat™ 0.6/1.0 on 300 gold mesh for high magnifications. The Au-flat™ range offers biocompatible Cryo-EM grids and we have them in stock!

Extended Cap Analoga portfolio
GP3A and m7GP3A are now available for in vitro transcription experiments with A-initiating T7 class II phi 2.5 promotor-containing DNA templates.

Active Furin and PC7 proteins for COVID-19 research
Find out how Furin and PC7 can help fight the COVID-19 pandemic! Read more...

Fission impossible: Non-hydrolyzable nucleotide analogs
Non-hydrolyzable nucleotides are essential tools for biochemical studies. More than 80 new analogs are now available as catalog products. Read more...

Why freeze-dried PCR mixes?
Freeze-dried/lyophilised PCR mixes are stable at ambient temperatures and allow point-of-care use without any refrigerating infrastructure. Read more...

One-step 3'-End RNA Labeling with AZDyes
One-step labeling of short 3'-End AZDye modified RNA is now easily achievable.

LEXSY - Custom protein expression service
Are you interested in protein expression, but lack the time or manpower to realize your project? Try our custom protein expression service!

Phosphorothioate-modified (m)RNA: Improved stability & enhanced translation efficiency
Phosphorothioate-modified (m)RNA is conveniently prepared by enzymatic incorporation of NTPαS thus generating (m)RNA with improved stability and translation efficiency profile. Read more...

Legumain: A ready-to-use Asparaginyl Endopeptidase
Learn more about human Legumain, a specific peptidase for asparagines and aspartates – perfect for Digestion Proteomics and targeted Drug Delivery!

LEXSY – The antigen production factory
Producing functional, correctly folded antigens is crucial for immunization experiments as well as structure determination. LEXSY can help you produce these antigens – from single proteins to complete virus-like particles. Read more...

LEXSY for difficult-to-express proteins
Complex proteins are often poorly expressed in prokaryotic expression systems. With LEXSY you can tackle these difficult proteins with a eukaryotic host – but with all the ease and simplicity known from prokaryotic cells. Read more...

XP Screens: Crystal Screening with TEW - The Protein Crystal Glue
The Anderson-Evans Polyoxotungstate [TeW6O24]6- (TEW) is a universal and flexible crystallization additive that is integrated in our XP Screens for improved crystal quality and resolution. Read more...

Bulk Scale Virus RNA processing!
Meet Jena Bioscience! We give you 5 compelling reasons why Jena Bioscience is your reliable manufacturer & partner when it comes to reagents for purification and amplification of viral RNA! Let us persuade you!

XP Up Screen: For successful screening with TEW - The Protein Crystal Glue
The XP Up Screen is a new crystallization screen specifically developed for high TEW concentrations up to 10 mM.

Selective mitochondrial DNA staining: PdG
Visualize cellular mtDNA clearly and selectively with PdG (6-O-propynyl-dG) and see the advantages over 5-ethynyl-dU! Read more...

Efficient enzymatic preparation of 2'F-modified Aptamers
RNA synthesis kits with a T7 RNA polymerase triple mutant are now available for efficient 2'F-modified Aptamers preparation: 2'F-dUTP-based, 2'F-dCTP-based, 2'F-dGTP-based, 2'F-dATP-based

Mind your sugars: Antigen glycosylation in LEXSY
When producing antigens, proper glycosylation is often the key to success. LEXSY is able to recognize glycosylation sites and provide proteins with correct glycan patterns.

Efficient dsRNA synthesis for RNAi applications
Double-stranded RNA (dsRNA) is a key molecule in RNA interference (RNAi)-mediated gene silencing at the mRNA level. Large amounts of dsRNA can be efficiently synthesized via in vitro transcription.

Reduce false positives with hot start PCR
Non-specific PCR products can form through mispriming before heating begins. Hot start polymerases are inhibited at room temperature, reducing non-specific amplification. Learn how to set up your PCR to increase specificity and reduce false positives!

Increase 5' homogeneity of in vitro transcribed RNA
Structural investigations of RNA require a homogenous RNA preparation. Learn how to reduce in vitro transcription-caused 5' heterogeneity!

FORMOscreen®: The best FDA/EMA-approved formulations for your antibody
The FORMOscreen® is a novel screen that makes it easy to find the most suitable buffer for any antibody. It contains 96 buffers from carefully selected, FDA/EMA-approved antibody formulations that can be screened with high-throughput methods such as DSF and nanoDSF, or with any other method of choice.

RNA Amplification: Keep control!
Be it because you require large quantities of reagents, for lowering costs or simply the fact that you prefer to design your own assay. Find out how Jena Bioscience can provide you with maximum flexibility in RT-qPCR reactions!

RNA-Protein Photocrosslinking: Site- and sequence-specific Tracking
Explore the advantages of using 4-Thio-uridine containing products to identify RNA-protein interactions both in cells and in vitro!

LEXSY in vitro translation: High yield, low cost
Producing research amounts of recombinant proteins of interest by in vitro translation is often fast and convenient however, suffers from a reputation of being expensive. Using LEXSY in vitro cuts reaction costs down to € 2.50 per reaction while offering a fully eukaryotic protein expression and modification machinery.

Distribution partner in Kuwait
We welcome Medvision as our official distribution partner in Kuwait. For details, see here!

New Distributor in China
We welcome Bioinborn Scientific as a new distributor in China. Find their contact details here!

New: HighYield T7 RNAi Kit
HighYield T7 RNAi Kit is now available for the production of dsRNA >200 bp that can subsequently be used for RNA interference (RNAi) applications.

Poly (A) carrier RNA: Improved viral RNA recovery
Poly (A) carrier RNA facilitates quantitative purification of low RNA amounts. Read more...

New and in stock: Au-flat™ Holey Gold Films
They are stronger than carbon films, bio-compatible and reduce beam-induced motion during imaging - learn more here.

New: Highly concentrated T7 RNA Polymerase version
T7 RNA Polymerase (HC) is now available for set-up and optimization of individual high yield in vitro transcription reactions.

Now available: Poly(A) carrier RNA
We now offer Poly(A) carrier RNA for quantitative purification of RNA and DNA.

Viral proteins expressed in LEXSY
Viral proteins are often hard to express in conventional expression systems. See how LEXSY can help!

Distribution partner in Ethiopia
We welcome Biogene Importer as our distributor in Ethiopia! Find their complete contact details here.

Distributor in Jordan
We are proud to present our new Distributor in Jordan, Ginsta Drug Store. Find their contact details here. Interested to join our family of distribution partners? Then please contact us!

Jena Bioscience bei JenaTV
Der Lokalsender JenaTV berichtete am 22. April über Jena Bioscience. Das Video kann in der Mediathek von JenaTV angesehen werden.

New Distributor in Turkey and Azerbaijan
We are happy to welcome Genoks Technology Co. Ltd. to our family of sales partners! Genoks is taking care of our customers in Turkey and Azerbaijan. Find their contact details here!

Optimized and validated for Covid-19: SCRIPT RT-qPCR ProbesMaster UNG
Check out our RT-real-time PCR master mix based on dual labeled fluorescent probes for detection in 1.5 hrs!

Distributor in Oman
We are proud to present our new Distributor in Oman, GLOBAL ENVIROQUEST LLC. Find their contact details here. Interested to join our family of distribution partners? Then please contact us!

Efficient RNA Labeling with AZDyes (structural analogs of Alexa Fluor® dyes)
Efficient preparation of AZDye-labeled RNA is now easily achievable via in vitro transcription. Read more...

The gold standard in viral dsRNA detection: Monoclonal J2, K1 & K2 antibodies
Anti-dsRNA monoclonal antibodies are efficient tools for the detection of dsRNA both in cell culture and FFPE samples. Read more...

Monoclonal antibodies for (viral) dsRNA detection
We now offer the Anti-dsRNA monoclonal antibodies J2, K1 and K2.

AZDye (structural analogs of Alexa Fluor® Dyes) RNA Labeling Kits
Efficient AZDye RNA labeling is now feasible with our HighYield T7 AZDye 488-, HighYield T7 AZDye 555-, HighYield T7 AZDye 594- and HighYield T7 AZDye 647-RNA Labeling Kits.

Creating the desired post-translational modifications with LEXSY
Is your recombinant protein lacking the necessary post-translational modifications (PTMs)? See how LEXSY can help!

Information regarding Corona virus
Jena Bioscience has implemented measures to keep all internal processes up and running and to avoid further spread of Corona virus. Incoming orders will be delivered as usual, work on custom projects will continue and customer support is available at the usual business hours. We ask our customers, partners and suppliers to inform us about any changes on their side that might have an effect on mutual business. Please contact us with any questions or concerns.

Explore the ATP binding proteome!
Explore the ATP binding proteome with our new Acyl-ATP probes, ATP-acetyl-hex-Biotin and ATP-acetyl-Desthiobiotin!

New: HighYield T7 P&L RNA Synthesis Kit
We now offer a HighYield RNA Synthesis Kit based on a modified T7 RNA Polymerase that has been associated with decreased abortive transcription, increased transcript 5' homogeneity and increased 5' incorporation efficiency of GTP analogs.

Modified mRNA synthesis beyond the classics
5’-capping and epigenetic nucleotide modifications are critical for efficient translation and reduced immunogenicity of synthetic mRNA. The classic combination of modifications consists of ARCA, 5-methylcytidine and pseudouridine. Promising extensions of the mRNA modification toolbox are available.

Rapid qPCR diagnostic test for pork and horse DNA contamination
The demand for Halal-tested products is constantly increasing. Customers must be assured that products they are consuming are free of meat contaminants (e.g. horse or pork). At Medlab Middle East in Dubai we launch a new series of Meat Detection Kits.

IR dye - labeled DNA Probes
We now offer ATTO680 NT Labeling kit for the preparation of ATTO680-labeled DNA probes via nick translation.

Nourseothricin (clonNAT) – Flexible, reliable and affordable antibiotic selection
Need a selection antibiotic for your organism? Nourseothricin can be used for selection of over 100 different species from all kingdoms of life – at affordable costs! Learn more...

12 New non-hydrolyzable nucleotides available!
We have expanded our portfolio of non-hydrolyzable nucleotides with 12 new compounds to study protein-protein interactions, structure and dynamics of protein-nucleotide complexes, and NTPase kinetics. Find more information here!

Probes for ATP binding proteins
We now offer Probes for ATP binding proteins: ATP-acetyl-hex-Biotin and ATP-acetyl-Desthiobiotin.

DNA probes up to 4 kbp: Efficient Cy®-, ATTO™- or AZDye-labeling
PCR is the method of choice for DNA probe labeling if template amounts are limited or labeling of a sequence-specific DNA fragment is required. Read more...

Cryo-EM grids available
Single particle electron cryo-microscopy (cryo-EM) is a powerful technique to determine the structures of protein complexes down to atomic resolution. The sample is applied onto a holey carbon film and is then flash-frozen in liquid ethane. C-flat™ holey carbon films are superflat sample supports providing flat and even amorphous ice. And: they are in stock for immediate delivery! Learn more...

Northern Blots: 0.05 fmol detection limit with near-IR RNA Probes
Current near-IR fluorescent RNA probes use dye-labeled nucleotides with only moderate sensitivity. Use copper-free CLICK labeling for increased sensitivity. Learn more here!

cGAMPs: The Second Messengers you need
cGAMPs are cyclic dinucleotides (CDNs) consisting of a 12-or-13-membered ring scaffold and two ribonucleotides. To date, two cGAMPs have been discovered in nature - 2‘,3‘-cGAMP and 3‘,3‘-cGAMP. Join the exciting field of cyclic dinucleotide signaling and expand your molecular toolbox!

CRISPR/Cas: RNA-guided gene targeting
CRISPR/Cas systems are the most flexible and efficient site-directed gene targeting tools currently available. Learn more!

SpCas9-specific sgRNA Synthesis
We now offer a convenient and efficient HighYield T7 sgRNA Synthesis Kit (SpCas9) for cloning-free preparation of SpCas9-specific sgRNA. Individual (s)gRNA-encoding T7 DNA templates (e.g with a different Cas9 scaffold or for different Cas endonucleases) can efficiently be in vitro transcribed with the HighYield T7 RNA Synthesis Kit.

LEXSY for Membrane Transporters
Membrane transporters are difficult to produce in most expression systems. With LEXSY you can express and investigate them.

3'-End RNA-modifying enzymes
We now offer the RNA-modifying enzyme Yeast Poly(A) Polymerase.

Adapted to your workflow!
Looking for lab reagents, have you ever been overwhelmed by eternally long product lists? And finally you didn’t even find what you were looking for? We’ll put an end to that and provide a helpful tool for more clarity: your workflow. Take the journey and explore the JBS World of Molecular Biology for yourself!

Rethinking routine PCR
Despite the variety, many scientists choose their well-known PCR mixes for routine applications without questioning. Those were recommended by fellow lab members or identified in test series some years ago. But are they still the gold standard today?

Back in our catalog!
Highly efficient octadiynyl labels for enzymatic incorporation into DNA: C8-Alkyne-dCTP and C8-Alkyne-dUTP are utilized by numerous DNA polymerase and give excellent labeling results in CuAAC.

Interested in ARCA-capped and internally modified RNA?
We now offer HighYield kits for synthesis of ARCA-capped and/or 5-methylcytosine & pseudouridine-modified (m)RNA.

Biotin-16-ddUTP is now available for:
3'-end labelingMALDI-TOF MS-based SNP typing assaystandard nick translation reaction for tumor DNA labelling during comparative genomic hybridizationBiotinylation of in vitro transcribed tmRNA during surface plasmon resonance (SPR) technique

Available again!
2-Ethynyl-Adenosine-NAD+ (2-EA-NAD+), a clickable probe for the detection of protein ADP-ribosylation, is now back in our catalog.

New HighYield T7 RNA Labeling Kits
HighYield T7 RNA Labeling Kits for preparation of Digoxigenin, Biotin and fluorescent RNA probes are now available. The single nucleotide format offers maximum optimization flexibility.

New Bst Turbo Polymerase
Check out our new Saphir Bst 2.0 Turbo Polymerase with additional DNA-binding domain for ultra-fast amplification!

New LEXSY Brochure
Our new LEXSY Brochure has just been released!

Swiss Army Knives for NTPase Analysis
BODIPY® FL NTPs are multipurpose tools forNucleotide binding studies on Gα, Ras, FHIT and RNAse L proteinsGTPase activity assaysActivity-based covalent labeling of bacterial two-component systemsSee how it works!

New viral proteins
We expanded our portfolio by numerous new viral proteins suitable for immunoassays. Find more information here!

HighYield T7 RNA Synthesis Kit
Now available! Our HighYield T7 RNA Synthesis Kit is designed for the efficient production of unmodified and modified RNA.

Four times faster than PCR!
Here we introduce our genetically optimized Saphir Bst2.0 Polymerase that allows even faster amplification at constant temperature. Receive results in less than 30 min time and reduce costs by half!

Pyrimidyl-Tetrazines
Now available! Our new class of tetrazine-dye reagents new class of tetrazine-dye reagents shows high reaction rates and permits fluorescent labeling with diminished background staining.

DADPS and Disulfide Biotin Azides
Cleavable biotin-azid-conjugates for capture and release approaches under acidic and reductive conditions have now been added to our catalog!

Safe Storage and Shipping of Cryo-EM Samples
From Cryo-EM Grid Boxes to Dry Shippers: Get the complete product package to safely store and ship your Cryo-EM Samples!

Saphir Bst Polymerase
Saphir Bst Polymerase is a genetically improved Bst enzyme for rapid amplification of DNA at constant temperature. Its high strand displacement and polymerization activity allows the detection of a target gene within 10-30 minutes.

Time to wake up
The World Health Organization defines 20 neglected tropical diseases (NTDs). They mainly affect the poorest of the poor - and this is precisely why they receive little attention in research. Learn about our support in fighting sleeping sickness!

LEXSY in Kinetoplastid Research
Researching pathogenic parasites can be difficult due to strict laboratory requirements and the risk of infection. LEXSY can be used to investigate kinetoplastids in a safe and convenient way.

Removal of contaminating DNA & RNA
During protein purification it is essential to remove residual nucleic acids efficiently. This is most readily achieved by non-site specific, enzymatic DNA/RNA degradation using Turbo Nuclease.

Get the best ice!
Protein sample vitrification for Cryo-EM is still a major bottleneck. The Cryo-EM V-Kit – our Vitrification Starter Kit – can help in this crucial step!

New Section: RNA Technologies
Looking for products to support your RNA research? Then have a look here!

Fission Impossible: Non-hydrolyzable nucleotide analogs
To study:protein-protein interactionsstructure and dynamics of protein-nucleotide-complexesNTPase kinetics Learn more!

New Section: RNA Technologies
Looking for products to support your RNA research? Have a look at our new RNA Technologies section. Our product portfolio will constantly be extended. Want to stay updated? Sign up for our RNATech newsletter or contact us at rnatech@jenabioscience.com!

Extended Nick Translation Kit Portfolio
We now offer AZDye 555-based and AZDye 647-based Nick Translation Labeling Kits. AZDye 555 and AZDye 647 are structural analogs of Alexa Fluor® 555 and Alexa Fluor® 647, respectively. Check out our complete portfolio of Biotin/Digoxigenin-based and Fluorescent Nick Translation Kits as well.

LEXSY: Membrane Protein Expression & Crystallization
Integral membrane proteins are hard to express with common recombinant expression systems. Learn how LEXSY can help!

Shining a Spotlight on Nucleotide-Protein Interactions
Fluorescent nucleotide conjugates are analytical tools with exceptional versatility. By covering a plethora of fluorescence-based techniques they are applied as drug screening probes, in cytoskeletal imaging and in nucleotide-protein interaction studies. Learn more!

Not just talking!
With your purchases you become part of stories that go far beyond the daily business. Stories of helpfulness, hunger for education and cosmopolitanism. None of this would be possible without your loyalty. Many thanks for that!

Nick Translation-based DNA Probe Labeling
Looking for reliable and convenient Nick Translation Labeling Kits? Check out our Digoxigenin, Biotin and Fluorescent Nick Translation Kit portfolio!

LNA-NTPs
LNA-ATP, LNA-GTP, LNA-CTP and LNA-UTP for DNA and RNA incorporation studies are now available.

Nourseothricin (clonNAT): Antibiotic of choice for long-term cultivation
Antibiotic instability is often a problem in long-term cultivation experiments. Nourseothricin entirely circumvents this problem. Learn more here:

Nucleotide Chemotherapeutics – A Success Story Goes On!
Antiviral and Cytostatic Nucleotide Analogs toStudy pharmacologyElucidate metabolic pathwaysImprove the potencyCheck out our range of nucleotide chemotherapeutic derivatives!

AZDyes (structural analogs of Alexa Fluor® dyes)
Looking for photostable, affordable fluorescent dyes? Check our AZDye product portfolio!

Expression and Crystallization of Plant Proteins from LEXSY
Want to express plant proteins, but E. coli expression doesn't work? Click below for successful examples of expression, crystallization and structure elucidation of plant proteins from LEXSY!

4-Seleno-dTTP: NGS-based mapping of m6A-modified RNA sites
4SedTTP permits the identification of methylated adenosinesat single nucleotide resolutionwithout antibodiesin an NGS-based approachHow it works:

4-Selenothymidine-5'-triphosphate
4SedTTP for precise antibody-independent m6A identification is now available.

Nucleotides & qPCR: Easy online Search
Looking for nucleotides based on their structure or for a specific application? Want to find the most suitable qPCR mix for your assay?

New Brochure "Lyophilized Reagents"
No fridge required – learn more about our Ready-to-Use PCR Lyophilisates in our new brochure "Lyophilized Reagents"!

New function: Get individual CofA yourself!
You require a CofA for a product you ordered from Jena Bioscience? Now you can download it yourself!

Hapten-modified Nucleotides for DNA/RNA Labeling
New brochure available - download it here!

dNTP Guide – High Performance Nucleotides
Because nucleotides don't get better than this. Click here!

Online Search Tools
Now online: Check out our easy Search & Selection Tools forChemical StructuresDNA/RNA LabelingPCR ProductsFluorescent Nucleotides

New Pathways to DNA Amplification!
Imagine... ...no lab skills are needed to reproduce genetic material ...no lab is required to amplify and analyse DNA ...anyone can perform DNA amplification in less than 30 minutes

New in Click Chemistry: 2'-Azido-2'-dATP
We added 2'-Azido-2'-dATP to our Click Chemistry section. For more details please click here.

Di-Adenosine Polyphosphates: Bacterial Signaling Molecules
The mode of ApnA function in bacterial signaling is awaiting its elucidation. Click to see what our compounds can contribute!

Creating the desired post-translational Modifications with LEXSY
Is your recombinant protein lacking the necessary post-translational modifications (PTMs)? See how LEXSY can help!

Large Dimension Lipidic Mesophase
A size revolution in lipidic cubic phase crystallization! Learn how to provide enough space for your protein to crystallize...

Jena Bioscience News Blog
Stay informed about what's new at Jena Bioscience with our News Blog, allowing you to filter news messages by your area of interest. Check it out here!

Why are you still using radioactively labeled Probes?
If you’re running experiments like Northern and Southern blots, or EMSA, you’re probably using radioactively labeled probes, right? There’s good news and bad news. The bad news is that radioactively labeled probes have a limited half-life and require special laboratory equipment... DISCOVER THE GOOD NEWS!

New: 3' End Oligonucleotide Labeling Kits
3' End Oligonucleotide Labeling Kits for preparation of Biotin- or Digoxigenin-labeled ssDNA/oligonucleotide probes are now available.

High Concentration Biotin-11-UTP
We now offer 75 mM Biotin-11-UTP in addition to our standard 10 mM Biotin-11-UTP solution.

FSBA and FSBG: Universal Traps for Triphosphate-Cleaving Enzymes
Probing ATPases, G-Proteins, Kinases, and Polymerases with Sulfonyl Fluoride Nucleosides – See how it can help your research!

Biotin-14-dATP and -dCTP for Hi-C Experiments
Hi-C experiments allow analyses of spatial genome organization. Adjacent genome regions are tagged by enzymatic biotinylation using Biotin-14-dATP or Biotin-14-dCTP and subsequently identified by (next generation) sequencing.

Get the best out of your Crystals
You put in a lot of work getting crystals. Now is the time to prevent crystal damage, simplify cryoprotection and reduce background scattering to get the best possible diffraction data.

c-di-AMP – The Messenger You Can't Ignore
Research on bacterial second messengers has recently experienced tremendous progress, and cyclic di-AMP (c-di-AMP) is one of the rising stars.

New DNA/RNA labeling nucleotides
We now offer Biotin-14-dCTP, Biotin-11-ATP and dUTP-XX-ATTO-425 for enzymatic DNA/RNA labeling. Nucleotide Selector for DNA/RNA Labeling

Photostable CLICK dyes
(Picolyl-)Azide, Alkyne and DBCO-functionalized versions of AZDye 488 (structural analog of Alexa Fluor®488) and AZDye 594 (structural analog of Alexa Fluor®594) are now available.

Now available: c-di-AMP
cyclic-di-AMP - The pleiotropic bacterial second messenger now adds to our cyclic-di-Nucleotide portfolio.