Feb 19, 2024
A new generation of GTP analogs labeled with 5-FAM show improved hydrolytic stability and binding affinity for Gαi1 protein compared to commonly used MANT and BODIPY FL GTPγS. Read more...
Jul 12, 2023
We now offer a selection of 13C, 15N, 19F and 2H labeled RNA phosphoramidites and NTPs.
Mar 23, 2023
Efficient preparation of abberior® STAR dye-labeled RNA is now easily achievable via in vitro transcription. Read more...
Mar 18, 2023
Select one of our catalog products
UTP labeled with abberior® STAR 580
UTP labeled with abberior® STAR RED
dUTP labeled with abberior® STAR 580
dUTP labeled with abberior® STAR RED
or contact us if you are interested in a different abberior® dye-nucleotide conjugate.
Jan 25, 2023
Replacement of Uridine with N1-Methylpseudouridine has been utilized in the COVID-19 mRNA vaccines developed by both Pfizer-BioNTech and Moderna.
Research suggests that incorporation of N1-Methylpseudouridine increases mRNA vaccine effectiveness through enhanced protein expression combined with low immunogenicity. Read more...
Nov 22, 2022
Double-stranded RNA (dsRNA) is a major impurity of therapeutic mRNA produced by in vitro transcription. Impurity levels of this transcriptional by-product need to be tightly monitored in mRNA production lots to ensure efficient mRNA expression and to reduce the risk of undesired high immunogenicity.
May 17, 2022
Identify and isolate O-GlcNAc modifications on glyco-proteins using UDP-GalNAz! Read more...
Feb 24, 2022
GP3A and m7GP3A are now available for in vitro transcription experiments with A-initiating T7 class II phi 2.5 promotor-containing DNA templates.
Jan 12, 2022
Non-hydrolyzable nucleotides are essential tools for biochemical studies. More than 80 new analogs are now available as catalog products. Read more...
Nov 18, 2021
One-step labeling of short 3'-End AF (Alexa Fluor®)-Dye modified RNA is now easily achievable.
Sep 21, 2021
Phosphorothioate-modified (m)RNA is conveniently prepared by enzymatic incorporation of NTPαS thus generating (m)RNA with improved stability and translation efficiency profile. Read more...
Jan 12, 2021
Visualize cellular mtDNA clearly and selectively with PdG (6-O-propynyl-dG) and see the advantages over 5-ethynyl-dU! Read more...
Sep 09, 2020
Explore the advantages of using 4-Thio-uridine containing products to identify RNA-protein interactions both in cells and in vitro!
May 14, 2020
Explore the advantages of our new vinyl-modified nucleosides, which offer in combination with our labeled Pyrimidyl tetrazines the ability as high efficient metabolic reporters in RNA expression profiling!
Mar 12, 2020
Explore the ATP binding proteome with our new Acyl-ATP probes, ATP-acetyl-hex-Biotin and ATP-acetyl-Desthiobiotin!
Jan 08, 2020
We have expanded our portfolio of non-hydrolyzable nucleotides with 12 new compounds to study protein-protein interactions, structure and dynamics of protein-nucleotide complexes, and NTPase kinetics. Find more information here!
Dec 05, 2019
We now offer Probes for ATP binding proteins: ATP-acetyl-hex-Biotin and ATP-acetyl-Desthiobiotin.
Oct 24, 2019
cGAMPs are cyclic dinucleotides (CDNs) consisting of a 12-or-13-membered ring scaffold and two ribonucleotides. To date, two cGAMPs have been discovered in nature - 2‘,3‘-cGAMP and 3‘,3‘-cGAMP. Join the exciting field of cyclic dinucleotide signaling and expand your molecular toolbox!
Aug 12, 2019
Jul 05, 2019
2-Ethynyl-Adenosine-NAD+ (2-EA-NAD+), a clickable probe for the detection of protein ADP-ribosylation, is now back in our catalog.
Jun 13, 2019
BODIPY® FL NTPs are multipurpose tools for
Feb 21, 2019
To study:
Jan 18, 2019
Fluorescent nucleotide conjugates are analytical tools with exceptional versatility. By covering a plethora of fluorescence-based techniques they are applied as drug screening probes, in cytoskeletal imaging and in nucleotide-protein interaction studies. Learn more!
Nov 30, 2018
LNA-ATP, LNA-GTP, LNA-CTP and LNA-UTP for DNA and RNA incorporation studies are now available.
Oct 30, 2018
Antiviral and Cytostatic Nucleotide Analogs to
Sep 24, 2018
4SedTTP permits the identification of methylated adenosines
Sep 12, 2018
4SedTTP for precise antibody-independent m6A identification is now available.
Aug 31, 2018
Looking for nucleotides based on their structure or for a specific application?
Want to find the most suitable qPCR mix for your assay?
Jul 03, 2018
Because nucleotides don't get better than this. Click here!
Jun 21, 2018
We added 2'-Azido-2'-dATP to our Click Chemistry section. For more details please click here.
Jun 04, 2018
The mode of ApnA function in bacterial signaling is awaiting its elucidation. Click to see what our compounds can contribute!
May 16, 2018
If you’re running experiments like Northern and Southern blots, or EMSA, you’re probably using radioactively labeled probes, right?
There’s good news and bad news.
The bad news is that radioactively labeled probes have a limited half-life and require special laboratory equipment...
DISCOVER THE GOOD NEWS!
May 09, 2018
3' End Oligonucleotide Labeling Kits for preparation of Biotin- or Digoxigenin-labeled ssDNA/oligonucleotide probes are now available.
May 08, 2018
We now offer 75 mM Biotin-11-UTP in addition to our standard 10 mM Biotin-11-UTP solution.
Apr 18, 2018
Probing ATPases, G-Proteins, Kinases, and Polymerases with Sulfonyl Fluoride Nucleosides – See how it can help your research!
Apr 12, 2018
Hi-C experiments allow analyses of spatial genome organization. Adjacent genome regions are tagged by enzymatic biotinylation using Biotin-14-dATP or Biotin-14-dCTP and subsequently identified by (next generation) sequencing.
Feb 27, 2018
Research on bacterial second messengers has recently experienced tremendous progress, and cyclic di-AMP (c-di-AMP) is one of the rising stars.
Feb 16, 2018
We now offer Biotin-14-dCTP, Biotin-11-ATP and dUTP-XX-ATTO-425 for enzymatic DNA/RNA labeling.
Nucleotide Selector for DNA/RNA Labeling
Jan 16, 2018
cyclic-di-AMP - The pleiotropic bacterial second messenger now adds to our cyclic-di-Nucleotide portfolio.
