Jan 06, 2026

Explore our toolbox of reversible 3’-O-blocked nucleotides beyond their application in short-read sequencing-by synthesis-methods (SBS).
Dec 18, 2025
We now offer Thienoguanosine, a fluorescent isomorphic guanosine analog, ideal for 5´-end RNA labeling via in vitro transcription.
Dec 09, 2025

An expanding repertoire of linear and cyclic bacterial nucleotide second messengers has been discovered during the past years. Read more...
Nov 21, 2025

"The Panoptes system uses decoy cyclic nucleotides to defend against phage." - by Sullivan et al. (Nature, Oct 01, 2025) is our featured scientific article for November. Read the full story!
Nov 10, 2025

Discover how tCOTP is transforming RNA research and opens new possibilities for tracking mRNA delivery and function. Read more...
Oct 22, 2025

Our newly developed, linker-optimized fluorescent 7-Deaza-ATPs are now available as excellent substrates for T7 RNA Polymerase-mediated in vitro transcription. Read more...
Oct 15, 2025
Our portfolio of epigenetically relevant pyrimidines has been complemented by 5-Formyl-dCTP and 5-Carboxy-dCTP.
Oct 14, 2025
We extended our portfolio with the alarmones Adenosine-3‘-diphosphate-5‘-diphosphate (ppApp) and
Adenosine-3‘-diphosphate-5‘-triphosphate (pppApp). Check out our complete portfolio of nucleoside polyphosphates (pnNpn) as well!
Oct 08, 2025

"Replisome passage through the cohesin ring." - by Glaser et al. (Cell, Sep 16, 2025) is our featured scientific article for October. Find out more about it!
Sep 26, 2025

Mass-modified nucleotides allow unambiguous allele discrimination in mass spectrometry-based genotyping of single nucleotide polymorphisms (SNPs). Read more...
Sep 15, 2025

"FEN1 is critical for rapid single-strand break repair in G1 phase" - by Burdova et al. (Nucleic Acids Research, Aug 12, 2025) is our featured scientific article for September. Read why it matters!
Sep 05, 2025

Fluorescent reversible 3’-O-blocked dNTPs are key components of short read sequencing technologies such as reversible termination sequencing-by-synthesis (SBS). Read more...
Aug 14, 2025
In addition to ddNTPs, we now offer Acyclo-NTPs (Acyclo-ATP, Acyclo-CTP, Acyclo-GTP, Acyclo-5-Br-UTP) for mass spectrometry-based SNP genotyping.
Aug 11, 2025
Check out our α-[(6-Aminohexyl)imido]-AMPs labeled with various fluorescent dyes:
α-[(6-Aminohexyl)imido]-AMP-AZDye647
α-[(6-Aminohexyl)imido]-AMP-Cy5
α-[(6-Aminohexyl)imido]-AMP-AZDye555
α-[(6-Aminohexyl)imido]-AMP-Cy3
α-[(6-Aminohexyl)imido]-AMP-AZDye488
Aug 09, 2025
2’,5’-GpAp is now available that can be used as a negative control for 2’,3’-cGAMP due to its linear conformation.
Jul 09, 2025

Terminal fluorescently labeled dN6Ps have been established as key components of long-read sequencing technologies such as single-molecule real-time sequencing (SMRT).
Jul 04, 2025
We extended our portfolio of RNA Cap Analogs: m7GP32'-OmA
Jul 04, 2025
We now offer Fluorescently labeled 7-Propargylamino-7-Deaza-ATPs. They are excellent substrates for T7 RNA Polymerase - mediated in vitro transcription.
Apr 14, 2025
We extended our portfolio of 2'-O-methylated NTPs:
2'-O-MOE-ATP, 2'-O-MOE-GTP, 2'-O-MOE-CTP and 2'-O-MOE-UTP
Apr 03, 2025

Interested in cyclic dinucleotides (CDNs) and trinucleotides (CTNs) beyond the classics such as c-diGMP or c-diAMP? Read more...
Mar 04, 2025

7-Deaza-dGTP and N4-Methyl-dCTP are valuable nucleotide analogs used in amplification and sequencing applications of GC-rich DNA regions. Read more...
Feb 17, 2025
In addition to 2',3'-cCMP, we now offer 2',3'-cUMP, 2',3'-cAMP and 2',3'-cGMP as well.
Nov 12, 2024
Check out our gamma-phosphate Cy3-labeled dNTPs:
γ-(6-Aminohexyl)-dCTP-Cy3
γ-(6-Aminohexyl)-dTTP-Cy3
Contact us if you are interested in corresponding fluorescent conjugates.
Sep 09, 2024

Jena Bioscience now offers BHQ-1™-, BHQ-2™- and BHQ-10™- labeled nucleotides to quench fluorescence across different spectral ranges. Read more...
Aug 12, 2024

5’-Azido-puromycin allows visualization of newly synthesized proteins via copper-free CLICK labeling. Read more...
Jul 31, 2024

Katalin Karikó‘s and Drew Weissman‘s Nobel Prize-winning concept of nucleoside base modifications as basis for the development of effective mRNA vaccines has been successfully applied to self-amplifying RNA (saRNA). Read more...
Jul 03, 2024
zeta-(6-Aminohexyl)-dA6P
zeta-(6-Aminohexyl)-dG6P
zeta-(6-Aminohexyl)-dC6P
zeta-(6-Aminohexyl)-dT6P
Interested in corresponding fluorescent conjugates? Contact us!
Jul 03, 2024
We now offer the complete set of 3'-phosphate-dNTPs such as 3'-Phosphate-dATP, 3'-Phosphate-dCTP, 3'-Phosphate-dGTP and 3'-Phosphate-dTTP.
Jun 13, 2024

We extended our portfolio of Fluorescein-labeled nucleotides for non-radioactive labeling of nucleic acids.
May 27, 2024
Check out our DNP (Dinitrophenol)-labeled nucleotides for efficient non-radioactive labeling of RNA and DNA:
Aminoallyl-UTP-DNP
Aminoallyl-dUTP-DNP
Aminoallyl-CTP-DNP
Aminoallyl-dCTP-DNP
May 16, 2024

Cy3-,Cy5- and Biotin-labeled nucleotides with increased concentration have now been added to our catalog. Check out our portfolio here!
May 15, 2024
In addition to 7-Deaza-dGTP and
dITP, we now offer N4-Methyl-dCTP that can be used as dCTP substitute.
Feb 19, 2024

A new generation of GTP analogs labeled with 5-FAM show improved hydrolytic stability and binding affinity for Gαi1 protein compared to commonly used MANT and BODIPY FL GTPγS. Read more...
Mar 23, 2023

Efficient preparation of abberior® STAR dye-labeled RNA is now easily achievable via in vitro transcription. Read more...
Mar 18, 2023
Select one of our catalog products
UTP labeled with abberior® STAR RED
dUTP labeled with abberior® STAR RED
or contact us if you are interested in a different abberior® dye-nucleotide conjugate.
Jan 25, 2023

Evidence suggests that N1-Methylpseudouridine modification increases mRNA vaccine effectiveness. Read more...
Research suggests that incorporation of N1-Methylpseudouridine increases mRNA vaccine effectiveness through enhanced protein expression combined with low immunogenicity. Read more...
Nov 22, 2022

Double-stranded RNA (dsRNA) is a major impurity of therapeutic mRNA produced by in vitro transcription. Impurity levels of this transcriptional by-product need to be tightly monitored in mRNA production lots to ensure efficient mRNA expression and to reduce the risk of undesired high immunogenicity.
May 17, 2022
Identify and isolate O-GlcNAc modifications on glyco-proteins using UDP-GalNAz! Read more...
Feb 24, 2022
GP3A and m7GP3A are now available for in vitro transcription experiments with A-initiating T7 class II phi 2.5 promotor-containing DNA templates.
Jan 12, 2022

Non-hydrolyzable nucleotides are essential tools for biochemical studies. More than 80 new analogs are now available as catalog products. Read more...
Nov 18, 2021
One-step labeling of short 3'-End AZDye modified RNA is now easily achievable.
Sep 21, 2021

Phosphorothioate-modified (m)RNA is conveniently prepared by enzymatic incorporation of NTPαS thus generating (m)RNA with improved stability and translation efficiency profile. Read more...
Jan 12, 2021

Visualize cellular mtDNA clearly and selectively with PdG (6-O-propynyl-dG) and see the advantages over 5-ethynyl-dU! Read more...
Sep 09, 2020

Explore the advantages of using 4-Thio-uridine containing products to identify RNA-protein interactions both in cells and in vitro!
Mar 12, 2020

Explore the ATP binding proteome with our new Acyl-ATP probes, ATP-acetyl-hex-Biotin and ATP-acetyl-Desthiobiotin!
Jan 08, 2020

We have expanded our portfolio of non-hydrolyzable nucleotides with 12 new compounds to study protein-protein interactions, structure and dynamics of protein-nucleotide complexes, and NTPase kinetics. Find more information here!
Dec 05, 2019
We now offer Probes for ATP binding proteins: ATP-acetyl-hex-Biotin and ATP-acetyl-Desthiobiotin.
Oct 24, 2019

cGAMPs are cyclic dinucleotides (CDNs) consisting of a 12-or-13-membered ring scaffold and two ribonucleotides. To date, two cGAMPs have been discovered in nature - 2‘,3‘-cGAMP and 3‘,3‘-cGAMP. Join the exciting field of cyclic dinucleotide signaling and expand your molecular toolbox!
Aug 12, 2019
Jul 05, 2019
2-Ethynyl-Adenosine-NAD+ (2-EA-NAD+), a clickable probe for the detection of protein ADP-ribosylation, is now back in our catalog.
Jun 13, 2019

BODIPY® FL NTPs are multipurpose tools for
Feb 21, 2019

To study:
Jan 18, 2019
Fluorescent nucleotide conjugates are analytical tools with exceptional versatility. By covering a plethora of fluorescence-based techniques they are applied as drug screening probes, in cytoskeletal imaging and in nucleotide-protein interaction studies. Learn more!
Nov 30, 2018
LNA-ATP, LNA-GTP, LNA-CTP and LNA-UTP for DNA and RNA incorporation studies are now available.
Oct 30, 2018

Antiviral and Cytostatic Nucleotide Analogs to
Sep 24, 2018

4SedTTP permits the identification of methylated adenosines
Sep 12, 2018
4SedTTP for precise antibody-independent m6A identification is now available.
Aug 31, 2018

Looking for nucleotides based on their structure or for a specific application?
Want to find the most suitable qPCR mix for your assay?
Jul 03, 2018
Because nucleotides don't get better than this. Click here!
Jun 21, 2018
We added 2'-Azido-2'-dATP to our Click Chemistry section. For more details please click here.
Jun 04, 2018
The mode of ApnA function in bacterial signaling is awaiting its elucidation. Click to see what our compounds can contribute!
May 16, 2018

If you’re running experiments like Northern and Southern blots, or EMSA, you’re probably using radioactively labeled probes, right?
There’s good news and bad news.
The bad news is that radioactively labeled probes have a limited half-life and require special laboratory equipment...
DISCOVER THE GOOD NEWS!
May 09, 2018
3' End Oligonucleotide Labeling Kits for preparation of Biotin- or Digoxigenin-labeled ssDNA/oligonucleotide probes are now available.
May 08, 2018
We now offer 75 mM Biotin-11-UTP in addition to our standard 10 mM Biotin-11-UTP solution.
Apr 18, 2018
Probing ATPases, G-Proteins, Kinases, and Polymerases with Sulfonyl Fluoride Nucleosides – See how it can help your research!
Apr 12, 2018
Hi-C experiments allow analyses of spatial genome organization. Adjacent genome regions are tagged by enzymatic biotinylation using Biotin-14-dATP or Biotin-14-dCTP and subsequently identified by (next generation) sequencing.
Feb 27, 2018
Research on bacterial second messengers has recently experienced tremendous progress, and cyclic di-AMP (c-di-AMP) is one of the rising stars.
Feb 16, 2018
We now offer Biotin-14-dCTP, Biotin-11-ATP and dUTP-XX-ATTO-425 for enzymatic DNA/RNA labeling.
Nucleotide Selector for DNA/RNA Labeling
Jan 16, 2018
cyclic-di-AMP - The pleiotropic bacterial second messenger now adds to our cyclic-di-Nucleotide portfolio.