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Cell Labeling - Fluorescent Hormones

Estradiol Glow is the ovarian steroid hormone 17-β-Estradiol labeled with a novel low molecular weight orange/red fluorophore, thus retaining its chemical properties and its biological activity. This allows for a wide range of applications including

  • analysis of in vivo and in vitro steroid uptake in real time
  • monitoring of intracellular and subcellular steroid transport
  • studies on steroid-binding proteins
  • use as tracer for steroid immunoassays (to replace isotopes or enzymes)
  • photodynamic elimination of estrogen sensitive tissues and cells in experimental settings with possible future clinical implications

Estradiol Glow Bild

Figure 1: 1 µm section of 3T3 cells incubated with Estradiol Glow shows internalization and subcellualar compartimentalization.