Fluorescent Hormones

Estradiol Glow is the ovarian steroid hormone 17-β-Estradiol labeled with a novel low molecular weight orange/red fluorophore, thus retaining its chemical properties and its biological activity. This allows for a wide range of applications including

• analysis of in vivo and in vitro steroid uptake in real time
• monitoring of intracellular and subcellular steroid transport
• studies on steroid-binding proteins
• use as tracer for steroid immunoassays (to replace isotopes or enzymes)
• photodynamic elimination of estrogen sensitive tissues and cells in experimental settings with possible future clinical implications

Figure 1: 1 µm section of 3T3 cells incubated with Estradiol Glow shows internalization and subcellualar compartimentalization.