Since there is no such thing as a standard buffer for all proteins, success of purification and downstream processing of a particular protein of interest greatly depends on identification of a buffer environment that facilitates the protein's stability & homogeneity in solution. Thus, in most labs it has become routine to search for stabilizing conditions before starting time-consuming crystallization experiments. Choose your favorite from a number of screens.
Antibody formulation screen with 96 FDA- and EMA-approved conditions as starting points to develop preformulations for new therapeutic and diagnostic antibody candidates.
Determine a protein stabilizing environment by strictly categorizing screening into fundamental and specific factors.
Optimize the solubility of your protein sample prior to crystallization trials.
