12 New non-hydrolyzable nucleotides available!

Crucial cellular processes such as transport, motion and division are orchestrated by a highly diverse set of regulatory phosphatases.

To trap these enzymes in their various biologically relevant states, non-hydrolyzable analogs of nucleotides are ideally suited.

Jena Bioscience has more than two decades of experience in the preparation of non-hydrolyzable nucleotides, supplying researchers with > 80 catalog products (see Scheme 1) of this compound class. It is our mission to facilitate your work on:

• Identification of protein-protein interactions and enzyme substrates
• Elucidation of structure and dynamics of protein-nucleotide-complexes
• Kinetic analysis of nucleotide exchange reactions on NTPase

Scheme 1: Overview of Jena Bioscience's non-hydrolyzable nucleotides.

Questions or inquiries?

You haven’t found your desired non-hydrolyzable nucleotide yet? Please inquire at nucleotides@jenabioscience.com and benefit from our custom synthesis service!