» Sign in / Register

UDP-GalNAz

UDP-N-azidoacetylgalactosamine

Sodium salt

UDP-N-azidoacetylgalactosamine

Cat. No. Amount Price (EUR) Buy / Note
CLK-077 0,5 mg 167,48 Add to Basket/Quote Add to Notepad
Structural formula of UDP-GalNAz (UDP-N-azidoacetylgalactosamine, Sodium salt)
Structural formula of UDP-GalNAz

For research use only!

Shipping: shipped at ambient temperature

Storage Conditions: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.

Shelf Life: 12 months after date of delivery

Molecular Formula: C17H26N6O17P2 (free acid)

Molecular Weight: 648.37 g/mol (free acid)

Purity: ≥ 95 % (HPLC)

Form: white to off-white solid

Solubility: water, aqueous buffer pH 7-7.5

Applications:
Transfer of GalNAz moiety to GalNAc residues of proteins and monoclonal antibodies with ß1,4-galactosyltranferase mutant Y289L-Gal-T1 [1-2].
The azide-functionalized target can subsequently be detected via Cu(I)-catalyzed or Cu(I)-free Click Chemistry that offers the choice to introduce

  • a Biotin group (via Azides of Biotin or DBCO-containing Biotin, respectively) for subsequent purification tasks or
  • a fluorophore (via Azides of fluorescent dyes or DBCO-containing fluorescent dyes, respectively) for subsequent microscopic imaging

Related products:

Selected References:
[1] Hang et al. (2004) Probing glycosyltransferase activities with the Staudinger ligation. J. Am. Chem. Soc. 126(1):6.
[2] Qasba et al. (2008) Site-specific linking of biomolecules via glycan residues using glycosyltransferases. Biotechnol. Prog. 24(3):520.