For research use only!
Shipping: shipped at ambient temperature
Storage Conditions: store at -20 °C
Shelf Life: 12 months after date of delivery
Molecular Formula: C16H22N4O10
Molecular Weight: 430.37 g/mol
Purity: ≥ 90 % (LC/MS)
Form: off-white to grey amorphous solid
Solubility: DMSO, DMF, MeOH
Glycoconjugate synthesis monitoring by metabolic labeling
The tetraacetylated N-Azidoacetyl-galactosamine (Ac4GalNAz) provides a non-radioactive alternative for glycoconjugate visualization. It is cell-permeable, intracellularly processed and incorporated instead of its natural monosaccharide counterpart N-Acetylgalactosamine(GalNAc).
The resulting Azide-functionalized glycoconjugates can subsequently be detected via Cu(I)-catalyzed or Cu(I)-free Click Chemistry that offers the choice to introduce a Biotin group (via Azides of Biotin or DBCO-containing Biotin, respectively) for subsequent purification tasks or to introduce fluorescent group (via Azides of fluorescent dyes or DBCO-containing fluorescent dyes, respectively) for subsequent microscopic imaging.
Recommended concentration for metabolic labeling: 25-75 μM. This concentration range may serve as a starting point for an individual assay set-up.
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