N-azidoacetylgalactosamine-tetraacylated (Ac4GalNAz)
| Cat. No. | Amount | Price (EUR) | Buy / Note |
|---|---|---|---|
| CLK-1086-5 | 5 mg | 199,60 | Add to Basket/Quote Add to Notepad |
| CLK-1086-25 | 25 mg | 498,70 | Add to Basket/Quote Add to Notepad |
| CLK-1086-100 | 100 mg | 997,80 | Add to Basket/Quote Add to Notepad |
For general laboratory use.
Shipping: shipped at ambient temperature
Storage Conditions: store at -20 °C
Shelf Life: 12 months after date of delivery
Molecular Formula: C16H22N4O10
Molecular Weight: 430.37 g/mol
Exact Mass: 430.13 g/mol
CAS#: 653600-56-7
Purity: mass identification (ESI-MS)
Form: amorphous solid
Color: off-white to grey
Solubility: DMSO, DMF, MeOH
Applications:
Glycoconjugate synthesis monitoring by metabolic labeling
Description:
The tetraacetylated N-Azidoacetyl-galactosamine (Ac4GalNAz) provides a non-radioactive alternative for glycoconjugate visualization. It is cell-permeable, intracellularly processed and incorporated instead of its natural monosaccharide counterpart N-Acetylgalactosamine(GalNAc).
The resulting Azide-functionalized glycoconjugates can subsequently be detected via Cu(I)-catalyzed or Cu(I)-free Click Chemistry that offers the choice to introduce a Biotin group (via Azides of Biotin or DBCO-containing Biotin, respectively) for subsequent purification tasks or to introduce fluorescent group (via Azides of fluorescent dyes or DBCO-containing fluorescent dyes, respectively) for subsequent microscopic imaging.
Recommended concentration for metabolic labeling: 25-75 μM. This concentration range may serve as a starting point for an individual assay set-up.
