(Picolyl-) Azides of (desthio) biotinylation reagents can be used for the labeling of terminal Alkyne- and strained Alkyne (e.g. DBCO)-labeled biomolecules via Cu(I)-catalyzed Alknye-Azide (CUAAC) or Cu(I)-free strain-promoted Alkyne-Azide Click Chemistry (SPAAC) reaction, respectively.
A number of (desthio) biotinylation reagents with
| Label | (Picolyl) Azide |
|---|---|
| Biotin | Azide-PEG3-Biotin Biotin-Azide Picolyl-Azide-PEG4-Biotin |
| Biotin with chemically cleavable linker | Diazo Biotin-Azide Dde Biotin-Azide Diol Biotin-Azide |
| Biotin with photocleavable linker | Photocleavable Biotin-Azide |
| Desthiobiotin | Azide-PEG3-Desthiobiotin |
