Azide-containing (Desthio) Biotinylation Reagents

(Picolyl-) Azides of (desthio) biotinylation reagents can be used for the labeling of terminal Alkyne- and strained Alkyne (e.g. DBCO)-labeled biomolecules via Cu(I)-catalyzed Alknye-Azide (CUAAC) or Cu(I)-free strain-promoted Alkyne-Azide Click Chemistry (SPAAC) reaction, respectively.

A number of (desthio) biotinylation reagents with

• different solubility characteristics (PEG-linker for increased molecule solubility)
• different cleavability characteristics (chemically or photocleavable linker)