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3'-dGTP

3'-Deoxyguanosine-5'-triphosphate, Sodium salt

Cat. No. Amount Price (EUR) Buy / Note
NU-1145S 50 μl (10 mM) 123,24 Add to Basket/Quote Add to Notepad
NU-1145L 5 x 50 μl (10 mM) 360,95 Add to Basket/Quote Add to Notepad
Structural formula of 3'-dGTP (3'-Deoxyguanosine-5'-triphosphate, Sodium salt)
Structural formula of 3'-dGTP

For research use only!

Shipping: shipped on blue ice

Storage Conditions: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.

Shelf Life: 12 months after date of delivery

Molecular Formula: C10H16N5O13P3 (free acid)

Molecular Weight: 507.18 g/mol (free acid)

Exact Mass: 507.00 g/mol (free acid)

CAS#: 55968-37-1

Purity: ≥ 95 % (HPLC)

Form: clear aqueous solution

Concentration: 10 mM - 11 mM

pH: 7.5 ±0.5

Spectroscopic Properties: λmax 252 nm, ε 13.7 L mmol-1 cm-1 (Tris-HCl pH 7.5)

Applications:
Microtubule assembly[1]
Hydrolysis by tubulin and proteins[1]

Specific Ligands:

Affinity to RNA polymerase I and II[2]

Affinity to DNA primase[2]

Product Citations:
Please click the black arrow on the right to expand the citation list. Click publication title for the full text.

Selected References:
[1] Hamel et al. (1984) Deoxyguanosine nucleotide analogues: potent stimulators of microtubule nucleation with reduced affinity for the exchangeable nucleotide site of tubulin. Biochemistry 23 (22):5314.
[2] Shunji Izuta et al. (1996) 3'-Deoxyribonucleotides inhibit Eukaryotic DNA Primase1. J. Biochem. 119 (6):1038.
Rasmussen et al. (1993) In vivo transcriptional pausing and cap formation on three Drosophila heat schock genes. Proc. Natl. Acad. Sci. USA 90:7923.
Hamel et al. (1976) Interactions of Guanosine Triphosphate Analogues with Elongation Factor G of Eschericha coli. J. Biochem. 63:13894.