7-Methyl-guanosine-5'-monophosphate, Triethylammonium salt
For research use only!
Shipping: shipped on blue ice
Storage Conditions: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.
Shelf Life: 12 months after date of delivery
Molecular Formula: C11H16N5O8P (free acid)
Molecular Weight: 377.25 g/mol (free acid)
Exact Mass: 377.07 g/mol (free acid)
Purity: ≥ 95 % (HPLC)
Form: clear aqueous solution
Concentration: 10 mM - 11 mM
pH: 7.5 ±0.5
Spectroscopic Properties: λmax 258/280 nm, ε 9.8/8.0 L mmol-1 cm-1 (Tris-HCl pH 7.5)
Association to human scavenger decapping enzyme
Inhibition of methyltransferase activity
Please click the black arrow on the right to expand the citation list. Click publication title for the full text.
 Darzynkiewicz et al. (2007) Interaction of human decapping scavenger with 5-mRNA cap analogues: structural requirements for catalytic activity. Journal of Physics: Condensed Matter 19:285217/1.
 Magden et al. (2001) Virus-specific mRNA capping enzyme encoded by hepatitis E virus. J. Virology 75:6249.
Shen et al. (2001) Structural and thermodynamic behavior of eukaryotic initiation factor 4E in supramolecular formation with 4E-binding protein 1 and mRNA cap analogue, studied by spectroscopic methods. Chem Pharm Bull 49 (10):1299.
Carberry et al. (1989) A spectroscopic study of the binding of m7GTP and m7GpppG to human protein synthesis initiation factor 4E. Biochemistry 28 (20):8078.
Beemon et al. (1977) In vitro translation yields a possible Rous sarcoma virus src gene product. Proc Natl Acad Sci U S A. 74 (8):3302.