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Mant-dGTP

3'-O-(N-Methyl-anthraniloyl)-2'-deoxyguanosine-5'-triphosphate, Triethylammonium salt

Cat. No. Amount Price (EUR) Buy / Note
NU-212S 50 μl (10 mM) 120,23 Add to Basket/Quote Add to Notepad
NU-212L 5 x 50 μl (10 mM) 352,15 Add to Basket/Quote Add to Notepad
Structural formula of Mant-dGTP (3'-O-(N-Methyl-anthraniloyl)-2'-deoxyguanosine-5'-triphosphate, Triethylammonium salt)
Structural formula of Mant-dGTP

For research use only!

Shipping: shipped on blue ice

Storage Conditions: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.

Shelf Life: 12 months after date of delivery

Molecular Formula: C18H23N6O14P3 (free acid)

Molecular Weight: 640.33 g/mol (free acid)

Exact Mass: 640.05 g/mol (free acid)

CAS#: 124615-99-2

Purity: ≥ 95 % (HPLC)

Form: colorless to slightly yellow solution in water

Concentration: 10 mM - 11 mM

pH: 7.5 ±0.5

Spectroscopic Properties: λmax 252/355 nm, ε 22.6/5.7 L mmol-1 cm-1 (Tris-HCl pH 7.5), λexc 355 nm, λem 448 nm

Applications:
Resonance energy transfer studies (FRET)[1]
Enzyme kinetic studies[2]

Specific Ligands:

Bacillus anthraxis toxin edema factor[1]

EF-Tu[3]

Product Citations:
Please click the black arrow on the right to expand the citation list. Click publication title for the full text.

Selected References:
[1] Suryanarayana et al. (2009) Distinct interactions of 2'- and 3'-O- (N-methyl)anthraniloyl-isomers of ATP and GTP with the adenylyl cyclase toxin of Bacillus anthracis, edema factor. Biochemical Pharmacology 78 (3):224.
[2] Kettlun et al. (2005) Potato tuber isoapyrases:Substrate specifity, affinity labelling, and proteolytic susceptibility. Phytochemistry 66:975.
[3] Rodnina et al. (1995) Codon-dependent conformational change of elongation-factor tu preceding GTP hydrolysis on the ribosome. EMBO J. 14 (11):2613.
Hazlett et al. (1993) Solution dynamics of p21 (Ras)proteins bound with fluorescent nucleotides - a time-resolved fluorescence study. Biochemistry-US 32 (49):13575.