ADP - Solid
For research use only.
Shipping: shipped on gel packs
Storage Conditions: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.
Shelf Life: 12 months after date of delivery
Molecular Formula: C10H15N5O10P2 (free acid)
Molecular Weight: 427.20 g/mol (free acid)
Exact Mass: 427.03 g/mol (free acid)
Purity: ≥ 95 % (HPLC)
Form: solid
Color: white to off-white
Spectroscopic Properties: λmax 259 nm, ε 15.4 L mmol-1 cm-1 (Tris-HCl pH 7.5)
Applications:
Agonistic ligand, mainly for nucleoside receptor A1
Nucleoside-triphosphates can be converted by different membrane-bound phosphatases into nucleosides acting as nucleoside receptor ligands. In some cases nucleoside phosphates act also directly on nucleoside receptors.
Selected References:
Volonte et al. (2009) Membrane components and purinergic signalling: the purinome, a complex interplay among ligands, degrading enzymes, receptors and transporters. FEBS J. 276:318.
Yegutkin (2008) Nucleotide and nucleoside converting enzymes: Important modulators of purinergic signalling cascade. Biochim. Biophys. Acta 1783:673.
Williams et al. (1986) Effects of purine nucleotides on the binding of [3H]cyclopentyladenosine to adenosine A1-receptors in rat brain membranes. J. Neurochem. 47 (1):88.
| Cat. No. | Amount | Price |
|---|---|---|
| NU-1198-1G | 1 g | 101,00 € |
| NU-1198-5G | 5 g | 377,80 € |
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Scientific citations for Jena Bioscience nu-1198
8 scientific citations and 0 citation images found by Bioz.
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Primer- and template-independent RNA polymerization by terminal nucleotidyltransferase TENT4B
Nucleic Acids Research, 2026-09-23 · PMID:42703972
0450), CTP (N0450), and UTP (N0450) were obtained from New England Biolabs, ADP (
NU-1198 ), Cy5-ATP [γ-(6-aminohexyl)-ATP-Cy5 (NU-833-CY5)] and Cy5-GTP [γ-(6-aminohexyl)-GTP-Cy5 (NU-834-CY5)] were fromJena Bioscience , and AMP (A1752),GDP (G7127), UDP (94 330), and CDP (C9755) were from Sigma. For RNA substrate extension assays, reactions were performed using various NTPs or NDPs with rTENT4B or oth -
Mitochondrial carrier SLC25A34 links clock, diet, and temperature control of interorganellar lipid cycling
bioRxiv, 2026-06-04 · DOI:10.64898/2026.05.30.724257
PrePrint: .. Cell Culture Microplates (Agilent Technologies) in the amount 60000 cells/well.. Prior to the experiment, the cells were rinsed with the MiR05 media (see O2k respirometry) once and supplemented with MiR05 media containing the Seahorse XF Plasma Membrane Permeabilizer (Agilent Technologies) in 1 nM concentration, 2 mM ADP (
Jena bioscience :NU-1198 ) and 1 mMMgCl 2 .. Immediately after the measurements were started.Immediately after the measurements were .. -
Extension of replicative lifespan by synthetic engineered telomerase RNA in patient induced pluripotent stem cells.
Nature Biomedical Engineering, 2025-06-27 · PMID:40579489
Abstract: RNA engineering has yielded a new class of medicines but faces limitations depending on RNA size and function. Here we demonstrate the synthesis and enzymatic stabilization of telomerase RNA component (TERC), a therapeutically relevant long non-coding RNA (lncRNA) that extends telomere length and replicative lifespan in human stem cells. Compared with therapeutic mRNAs, engineered TERC RNA (eTERC) depends on avoiding nucleoside base modifications and incorporates a distinct trimethylguanosine 5' cap during in vitro transcription
