3'-O-(N-Methyl-anthraniloyl)-2'-deoxyguanosine-5'-diphosphate, Triethylammonium salt
| Cat. No. | Amount | Price (EUR) | Buy / Note |
|---|---|---|---|
| NU-205S | 30 μl (10 mM) | 157,60 | Add to Basket/Quote Add to Notepad |
| NU-205L | 5 x 30 μl (10 mM) | 461,70 | Add to Basket/Quote Add to Notepad |
For general laboratory use.
Shipping: shipped on gel packs
Storage Conditions: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.
Shelf Life: 12 months after date of delivery
Molecular Formula: C18H22N6O11P2 (free acid)
Molecular Weight: 560.35 g/mol (free acid)
Exact Mass: 560.08 g/mol (free acid)
CAS#: 127383-33-9
Purity: ≥ 95 % (HPLC)
Form: solution in water
Color: colorless to slightly yellow
Concentration: 10 mM - 11 mM
pH: 7.5 ±0.5
Spectroscopic Properties: λmax 252/355 nm, ε 22.6/5.7 L mmol-1 cm-1 (Tris-HCl pH 7.5), λexc 355 nm, λem 448 nm
Applications:
Resonance energy transfer to Trp in protein cdc42hs[1]
Conformational analysis of Ras-like protein[2]
Specific Ligands:
Ras-like GTP-binding protein Cdc42Hs[1, 2]
Selected References:
[1] Leonard et al. (1994) Investigation of the GTP-binding GTPase cycle of cdc42hs using fluorescence spectroscopy. Biochemistry 33 (40):12323.
[2] Nomanbhoy et al. (1996) Investigation of the GTP-binding GTPase cycle of Cdc42Hs using extrinsic reporter group fluorescence. Biochemistry 35 (14):4602.
Liu et al. (2008) Ras Is Required for the Cyclic AMP-Dependent Activation of Rap1 via Epac2. Molecular and cellular biology 28 (23):7109.
