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Mant-dGDP

3'-O-(N-Methyl-anthraniloyl)-2'-deoxyguanosine-5'-diphosphate, Triethylammonium salt

Cat. No. Amount Price (EUR) Buy / Note
NU-205S 30 μl (10 mM) 123,24 Add to Basket/Quote Add to Notepad
NU-205L 5 x 30 μl (10 mM) 360,95 Add to Basket/Quote Add to Notepad
Structural formula of Mant-dGDP (3'-O-(N-Methyl-anthraniloyl)-2'-deoxyguanosine-5'-diphosphate, Triethylammonium salt)
Structural formula of Mant-dGDP

For research use only!

Shipping: shipped on blue ice

Storage Conditions: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.

Shelf Life: 12 months after date of delivery

Molecular Formula: C18H22N6O11P2 (free acid)

Molecular Weight: 560.35 g/mol (free acid)

Exact Mass: 560.08 g/mol (free acid)

CAS#: 127383-33-9

Purity: ≥ 95 % (HPLC)

Form: colorless to slightly yellow solution in water

Concentration: 10 mM - 11 mM

pH: 7.5 ±0.5

Spectroscopic Properties: λmax 252/355 nm, ε 22.6/5.7 L mmol-1 cm-1 (Tris-HCl pH 7.5), λexc 355 nm, λem 448 nm

Applications:
Resonance energy transfer to Trp in protein cdc42hs[1]
Conformational analysis of Ras-like protein[2]

Specific Ligands:

Ras-like GTP-binding protein Cdc42Hs[1, 2]

Product Citations:
Please click the black arrow on the right to expand the citation list. Click publication title for the full text.

Selected References:
[1] Leonard et al. (1994) Investigation of the GTP-binding GTPase cycle of cdc42hs using fluorescence spectroscopy. Biochemistry 33 (40):12323.
[2] Nomanbhoy et al. (1996) Investigation of the GTP-binding GTPase cycle of Cdc42Hs using extrinsic reporter group fluorescence. Biochemistry 35 (14):4602.
Liu et al. (2008) Ras Is Required for the Cyclic AMP-Dependent Activation of Rap1 via Epac2. Molecular and cellular biology 28 (23):7109.