2',3'-O-Trinitrophenyl-guanosine-5'-triphosphate, Triethylammonium salt
|Cat. No.||Amount||Price (EUR)||Buy / Note|
|NU-220S||1 μmol||132,40||Add to Basket/Quote Add to Notepad|
|NU-220L||5 x 1 μmol||387,90||Add to Basket/Quote Add to Notepad|
For general laboratory use.
Shipping: shipped on gel packs
Storage Conditions: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.
Shelf Life: 12 months after date of delivery
Molecular Formula: C16H17N8O20P3
Molecular Weight: 734.27 g/mol
Exact Mass: 733.98 g/mol
Purity: ≥ 95 % (HPLC)
Spectroscopic Properties: λmax 252/408/470 nm, ε 24.1/26.5/18.3 L mmol-1 cm-1 (Tris-HCl pH 7.5), λexc 408/470 nm, λem 552 nm
BIOZ Product Citations:
Please click the arrow on the right to expand the citation list. Click publication title for the full text.
Spangler et al. (2011) Interaction of the diguanylate cyclase YdeH of Escherichia coli with 2', (3')-substituted purine and pyrimidine nucleotides. J. Pharmacol. Exp. Ther. 336 (1):234.
Suryanarayana et al. (2009) Differential Inhibition of Various Adenylyl Cyclase Isoforms and Soluble Guanylyl Cyclase by 2',3'-O- (2,4,6-Trinitrophenyl)- Substituted Nucleoside 5'-Triphosphates. J. Pharmacol. Exp. Ther. 330 (3):687.
Goettle et al. (2007) Molecular analysis of the interaction of Bordetella pertussis adenylyl cyclase with fluorescent nucleotides. Molecular Pharmacology 72 (3):526.
Sprang et al. (2006) Broad Specifity of Mammalian Adenylyl Cyclase for Interaction with 2',3'-Substituted Purine- and Pyrimidine Nucleotide Inhibitors. Mol. Pharmacol. 70:878.
Golczak et al. (2002) GTP-induced membrane binding and ion channel activity of annexin VI: is annexin VI a GTP biosensor? Biophys. J. 82:2737.
Chordia et al. (1998) Distances between the paclitaxel, colchicine, and exchangeable GTP binding sites on tubulin. Biochemistry 37:6636.
Randak et al. (1996) A recombinant polypeptide model of the second predicted nucleotide binding fold of the cystic fibrosis transmembrane conductance regulator is a GTP-binding protein. FEBS Lett. 398:97.
Baubichon-Cortay et al. (1994) Overexpression and purification of the carboxyl-terminal nucleotide-binding domain from mouse P-glycoprotein. Strategic location of a tryptophan residue. J. Biol. Chem. 269:22983.
Hoyer et al. (1986) Synthesis of 2',3'-O- (2,4,6-trinitrocyclohexadienylidine)guanosine 5'-triphosphate and a study of its inhibitory properties with adenylate cyclase. Arch. Biochem. Biophys. 245:369.
Hiratsuka (1985) A chromophoric and fluorescent analog of GTP, 2',3'-O- (2,4,6-trinitrocyclohexadienylidene)-GTP, as a spectroscopic probe for the GTP inhibitory site of liver glutamate dehydrogenase. J. Biol. Chem. 260:4784.