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TNP-ADP

2',3'-O-Trinitrophenyl-adenosine-5'-diphosphate, Triethylammonium salt

Cat. No. Amount Price (EUR) Buy / Note
NU-222S 1 μmol 123,24 Add to Basket/Quote Add to Notepad
NU-222L 5 x 1 μmol 360,95 Add to Basket/Quote Add to Notepad
Structural formula of TNP-ADP (2',3'-O-Trinitrophenyl-adenosine-5'-diphosphate, Triethylammonium salt)
Structural formula of TNP-ADP

For research use only!

Shipping: shipped on blue ice

Storage Conditions: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.

Shelf Life: 12 months after date of delivery

Molecular Formula: C16H16N8O16P2

Molecular Weight: 638.28 g/mol

Exact Mass: 638.01 g/mol

CAS#: 77450-67-0

Purity: ≥ 95 % (HPLC)

Form: orange lyophilised solid

Spectroscopic Properties: λmax 259/408/470 nm, ε 25.0/26.4/18.5 L mmol-1 cm-1 (Tris-HCl pH 7.5), λexc 408/470 nm, λem 552 nm

Selected References:
Sprang et al. (2006) Broad Specifity of Mammalian Adenylyl Cyclase for Interaction with 2',3'-Substituted Purine- and Pyrimidine Nucleotide Inhibitors. Mol. Pharmacol. 70:878.
Qu et al. (2003) Stoichiometry and Affinity of Nucleotide Binding to P-Glycoprotein during the Catalytic Cycle. Biochemistry 42:1170.
Plesniak et al. (2002) Probing the nucleotide binding domain of the osmoregulator EnvZ using fluorescent nucleotide derivatives. Biochemistry 41:13876.
Hirschman et al. (2001) Active site mutations in CheA, the signal-transducing protein kinase of the chemotaxis system in Escherichia coli. Biochemistry 40:13876.
Galletto et al. (2000) Interactions of nucleotide cofactors with the escherichia coli replication factor DnaC protein. Biochemistry 39:12959.
Weber et al. (1997) Binding of TNP-ATP and TNP-ADP to the non-catalytic sites of Escherichia coli F1-ATPase. FEBS Lett. 412:169.
Thomas et al. (1991) Cystic fibrosis transmembrane conductance regulator: nucleotide binding to a synthetic peptide. Science 251:555.
Kormer et al. (1982) Using 2' (3')-O-trinitrophenyl derivatives of adenine nucleotides to study the structure and mechanism of functioning of soluble mitochondrial ATPase. Eur. J. Biochem. 121:451.
Schafer et al. (1982) Interaction of high-affinity nucleotide binding sites in mitochondrial ATP synthesis and hydrolysis. Bioenerg. Biomembr. 14:479.
Tao et al. (1981) Excitation energy transfer studies on the proximity between SH1 and the adenosinetriphosphatase site in myosin subfragment 1. Biochemistry 20:5051.
Hiratsuka et al. (1977) Heterogeneous reaction of heavy meromyosin ATPase with 2' (or 3')-O- (2,4,6-trinitrophenyl)adenosine 5'-5'-triphosphate. J. Biochem. (Tokyo) 82:575.

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