N⁶-Methyl-dATP

For general laboratory use.

Shipping: shipped on gel packs

Storage Conditions: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.

Shelf Life: 12 months after date of delivery

Molecular Formula: C₁₁H₁₈N₅O₁₂P₃ (free acid)

Molecular Weight: 505.21 g/mol (free acid)

Exact Mass: 505.02 g/mol (free acid)

Purity: ≥ 95 % (HPLC)

Form: solution in water

Color: colorless to slightly yellow

Concentration: 100 mM - 110 mM

pH: 7.5 ±0.5

Spectroscopic Properties: λ_max 269 nm, ε 15.4 L mmol^-1 cm^-1 (Tris-HCl pH 7.5)

BIOZ Product Citations:

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Selected References:
Choi et al. (2016) The use of modified and non-natural nucleotides provide unique insights into pro-mutagenic replication catalyzed by polymerase eta. Nucleic Acids Res. 44 (3):1022.
Devadoss et al. (2007) Enhancing the 'A-rule' of translesion DNA synthesis: promutagenic DNA synthesis using modified nucleoside triphosphates. Biochemistry 46 (48):13752.
Ratel et al. (2006) N6-methyladenine: the other methylated base of DNA. Bioessays. 28 (3):309.
Kuwahara et al. (2003) Simultaneous incorporation of three different modified nucleotides during PCR. Nucleic Acids Res. Suppl. 3:37.