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JBScreen Wizard

Application

JBScreen Wizard is a highly effective random sparse matrix screen for crystallizing proteins, peptides, nucleic acids and macromolecular complexes. A large range of precipitants, buffers and salts allow a broad sampling of crystallization space at pH levels from pH 4,5 to 10,5.

Format

Bulk – 48, 96 or 192 screening solutions in 10 ml aliquots
HTS – 96 or 192 screening solutions delivered in a deep-well block, 1.7 ml per well

 

Individual Conditions of all screens are available in 10 ml as well as 100 ml volumes.

Selected Recent Literature Citations of JBScreen Wizard

  • Lim et al. (2020) Targeting the interaction of AIMP2-DX2 with HSP70 suppresses cancer development. Nat. Chem. Biol. 16:31.
  • Huang et al. (2019) The atomic-resolution crystal structure of activated [Fe]-hydrogenase. Nat. Catal. 2:537.
  • Dos Santos et al. (2017) Renaissance of protein crystallization and precipitation in biopharmaceuticals purification. Biotechnol. Adv. 35:41.
  • Hagiwara et al. (2016) Atomic-resolution structure of the phycocyanobilin:ferredoxin oxidoreductase I86D mutant in complex with fully protonated biliverdin. FEBS Letters 590:3425.