Dibenzocyclooctyne (DBCO)*-containing FLAG tag reagents can be used for the introduction of a FLAG-tag to Azide-tagged biomolecules via Cu(I)-free strain-promoted Alkyne-Azide Click Chemistry (SPAAC). Molecule solubility and efficient FLAG-tag detection is ensured by the integrated PEG-linker.
*DBCO is also known as ADIBO (= Azadibenzocyclooctyne) or DIBAC (= Dibenzoazacyclooctyne)
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