N1-Methylpseudo-UTP
For research use only.
Please centrifuge briefly before opening (volume ≤2 ml).
Shipping: shipped on gel packs
Storage Conditions: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.
Shelf Life: 12 months after date of delivery
Molecular Formula: C10H17N2O15P3 (free acid)
Molecular Weight: 498.17 g/mol (free acid)
Exact Mass: 497.98 g/mol (free acid)
CAS#: 1428903-59-6 (free acid)
Purity: ≥ 99 % (HPLC)
Form: solution in water
Color: colorless to slightly yellow
Concentration: 100 mM - 110 mM
pH: 7.5 ±0.5
Solubility: water
Spectroscopic Properties: λmax 271 nm, ε 8.9 L mmol-1 cm-1 (Tris-HCl pH 7.5)
Related products: HighYield T7 RNA Synthesis Kit, #RNT-101
Selected References:
Andies et al. (2015) N (1)-methylpseudouridine-incorporated mRNA outperforms pseudouridine-incorporated mRNA by providing enhanced protein expression and reduced immunogenicity in mammalian cell lines and mice. J. Control. Release 217:337.
| Cat. No. | Amount | Price |
|---|---|---|
| NU-890S | 10 μl (100 mM) | 52,00 € |
| NU-890L | 5 x 10 μl (100 mM) | 195,00 € |
| NU-890XL | 100 μl (100 mM) | 345,80 € |
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Scientific citations for Jena Bioscience nu-890
26 scientific citations and 0 citation images found by Bioz.
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Recoding by N 1 -methylpseudouridine guides rational mRNA vaccine design
Nature Communications, 2026-09-28 · PMID:42805987
.. by polymerase chain reaction (PCR) and transcribed by addition of T7 RNA polymerase (1.6 unit/μl), nucleotide triphosphates (ATP, NU-1010; GTP, NU-1012; CTP, NU1011; and either UTP, NU-1013, or m 1
ΨTP, NU-890 ; 3 mM each,Jena Bioscience ), RNase inhibitor (0.2 units/μl, moloX GmbH), E. coli pyrophosphatase (0.005 units/μl, New England Biolabs, M0361) in buffer (40 mM Tris-HCl (Sigma-Aldrich, 252859) pH 7.5, 15 mM MgCl 2 (Sigma-Aldrich, M9272), .. -
Creating bottom-up RNA transfer vehicles from synthetic protein assemblies.
Nature, 2026-09-02 · PMID:42686908
.. treatment was monitored after 24 h using an EVOS imaging device (Thermo Fisher Scientific).. In addition, in vitro-transcribed mTagBFP2 mRNA was produced as previously described, using
N1-methylpseudouridine (Jena BioScience ) or unmodified uridine.. A549-IFN-GFP reporter cells were treated with STV-C8 containing mTagBFP2 mRNA or LNPs containing modified .. -
Systematic benchmarking of dorado basecalling models for RNA modification detection with highly multiplexed nanopore sequencing.
Nucleic Acids Research, 2026-06-17 · PMID:42306945
.. pseudouridine-5′ - Triphosphate (pseudo-UTP, Trilink, N-1019) instead of UTP, 5-Methyluridine-5′ -Triphosphate (5-meUTP, Trilink, N-1024–1) instead of UTP, N1 -Methylpseudouridine-5′ - Triphosphate (me1 -UTP, Jena
Bioscience, NU-890S ) instead of UTP, 5-methylcytidine-5′ -Triphosphate (5- methyl-CTP Trilink, N-1014), 5-Hydroxymethylcytidine5′ -Triphosphate (5-hme-CTP, Trilink, N-1087), N 4-Acetylcytidine-5′ -Triphosphate ( N4 -Acetyl-CTP, Jena Bioscience, NU-988S) instead ..
