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Mant-ATPγS

2'/3'-O-(N-Methyl-anthraniloyl)-adenosine-5'-( γ -thio)-triphosphate, Triethylammonium salt

Cat. No. Amount Price (EUR) Buy / Note
NU-232S 20 μl (10 mM) 120,22 Add to Basket/Quote Add to Notepad
NU-232L 5 x 20 μl (10 mM) 352,14 Add to Basket/Quote Add to Notepad
Structural formula of Mant-ATPγS (2'/3'-O-(N-Methyl-anthraniloyl)-adenosine-5'-( γ -thio)-triphosphate, Triethylammonium salt)
Structural formula of Mant-ATPγS

For research use only!

Shipping: shipped on blue ice

Storage Conditions: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.

Shelf Life: 6 months after date of delivery

Molecular Formula: C18H23N6O13P3S (free acid)

Molecular Weight: 656.39 g/mol (free acid)

Purity: ≥ 90 % (HPLC)

Form: colorless to slightly yellow solution in water

Concentration: 10 mM - 11 mM

pH: 7.5 ±0.5

Spectroscopic Properties: λmax 255/355 nm, ε 23.3/5.8 L mmol-1 cm-1 (Tris-HCl pH 7.5), λexc 355 nm, λem 448 nm

Applications:
Inhibition of heart adenylyl cyclase AC5[1]
Inhibition of adenylyl cyclase from Bordetella pertussis[2]
FRET[2]

Selected References:
[1] Goettle et al. (2009) Characterization of Mouse Heart Adenylyl Cyclase. J. Pharmacol. Exp. Ther. 329 (3):1156.
[2] Goettle et al. (2007) Molecular analysis of the interaction of Bordetella pertussis adenylyl cyclase with fluorescent nucleotides. Molecular Pharmacology 72 (3):526.
Erdorf et al. (2011) Pharmacological characterization of adenylyl cyclase isoforms in rabbit kidney membranes. Naunyn Schmiedebergs Arch. Pharmacol. 383 (4):357.