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8-Oxo-dGDP

8-Hydroxy-dGDP

8-Oxo-2'-deoxyguanosine-5'-diphosphate, Sodium salt

8-Hydroxy-2'-deoxyguanosine-5'-diphosphate, Sodium salt

Cat. No. Amount Price (EUR) Buy / Note
NU-1158S 20 μl (10 mM) 117,35 Add to Basket/Quote Add to Notepad
NU-1158L 5 x 20 μl (10 mM) 343,76 Add to Basket/Quote Add to Notepad
Structural formula of 8-Oxo-dGDP (8-Hydroxy-dGDP, 8-Oxo-2'-deoxyguanosine-5'-diphosphate, Sodium salt)
Structural formula of 8-Oxo-dGDP

For research use only!

Shipping: shipped on blue ice

Storage Conditions: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.

Shelf Life: 12 months after date of delivery

Molecular Formula: C10H15N5O11P2 (free acid)

Molecular Weight: 443.20 g/mol (free acid)

Exact Mass: 443.02 g/mol (free acid)

Purity: ≥ 95 % (HPLC)

Form: clear aqueous solution

Concentration: 10 mM - 11 mM

pH: 7.5 ±0.5

Spectroscopic Properties: λmax 245 nm, ε 12.3 L mmol-1 cm-1 (Tris-HCl pH 7.5)

Selected References:
Kai et al. (2002) An oxidized nucleotide affects DNA replication through activation of protein kinases in Xenopus egg lysates. Nucl. Acids Res. 30 (2):569.
Canitrot et al. (2000) Nucleotide excision repair DNA synthesis by excess DNA polymerase beta: a potential source of genetic instability in cancer cells. FASEB J. 14 (12):1765.
Nampalli et al. (2000) Efficient synthesis of 8-oxo-dGTP: A mutagenic nucleotide. Bioorg. Med. Chem. Lett. 10 (15):1677.