6-Thio-guanosine-5'-diphosphate, Sodium salt
For research use only!
Shipping: shipped on blue ice
Storage Conditions: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.
Shelf Life: 12 months after date of delivery
Molecular Formula: C10H15N5O10P2S (free acid)
Molecular Weight: 459.26 g/mol (free acid)
Exact Mass: 459.00 g/mol (free acid)
Purity: ≥ 95 % (HPLC)
Form: solution in water
Color: colorless to slightly yellow
Concentration: 10 mM - 11 mM
pH: 7.5 ±0.5
Spectroscopic Properties: λmax 257 nm, ε 8.8 L mmol-1 cm-1 (Tris-HCl pH 7.5), λmax 342 nm, ε 24.8 L mmol-1 cm-1 (Tris-HCl pH 7.5)
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Karner et al. (2010) Determination of 6-thioguanosine diphosphate and triphosphate and nucleoside diphosphate kinase activity in erythrocytes: novel targets for thiopurine therapy? Ther. Drug Monit. 32 (2):119.
Weng et al. (1994) Hydrogen bond interactions of G proteins with the guanine ring moiety of guanine nucleotides. Protein Sci. 1:22.