7-Deaza-7-ethynyl-2'-deoxyadenosine (EdA)
For research use only.
Shipping: shipped at ambient temperature
Storage Conditions: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.
Shelf Life: 12 months after date of delivery
Molecular Formula: C13H14N4O3
Molecular Weight: 274.28 g/mol
Exact Mass: 274.11 g/mol
Purity: ≥ 95 % (HPLC)
Form: solid
Color: white to yellow
Spectroscopic Properties: λmax 237/279 nm, ε 11.2/11.1 L mmol-1 cm-1 (Methanol)
Selected References:
Neef et al. (2012) Metabolic labeling of DNA by purine analogues in vivo. Chembiochem. 13 (12):1750.
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Scientific citations for Jena Bioscience clk-099
3 scientific citations and 0 citation images found by Bioz.
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Daxx mediated histone H3.3 deposition on HSV-1 DNA restricts genome decompaction and the progression of immediate-early transcription
PLoS Pathogens, 2025-08-20 · PMID:40834051
.. propagated in RPE cells and titrated in U2OS cells, as previously described [ ].. The labelling and purification of single or double labelled HSV-1 virions with 5-Ethynyl-2’-deoxycytidine (EdC; Sigma-Aldrich, T511307) and
7-Deaza-7-ethynyl-2’-deoxyadenosine (EdA;Jena Bioscience ,CLK-099 ) was performed as described [ , ].. Briefly, RPE cells were infected with WT or ICP0-null mutant HSV-1 at a MOI .. -
De novo assembly of RNA m 6 A modification factors into viral genome-associated nuclear bodies drives HCMV RNA accumulation.
Cell Reports, 2025-06-24 · PMID:40560728
HCMV labeling and click chemistry Labeling of HCMV virions for click chemistry was performed using 5-Ethynyl-2 ′ -deoxycytidine (EdC; Sigma-Aldrich #T511307) and
7-Deaza-7-ethynyl-2 ′ -deoxyadenosine (EdA;Jena Bioscience #CLK-099 -
MX2 forms nucleoporin-comprising cytoplasmic biomolecular condensates that lure viral capsids.
Cell host & microbe, 2024-10-10 · PMID:39389033
.. derived from BHK cells as described above for the propagation of HSV-1(17+) Lox-CheVP26. ... After 14 h, 40 h, and 64 h cells were pulsedwith 0.5 mM5-Ethynyl-2’-deoxycytidine (EdA, #CLK-N003-10, JenaBioscience) and 0.5
mM7-Deaza-7-ethynyl-2’-deoxyadenosine (EdA, #CLK-099 ,Jena Bioscience ).. Extracellular virus was harvested when nearly all cells had rounded up (ca.Extracellular virus was ..
