CTP - Solution

For general laboratory use.

Shipping: shipped on gel packs

Storage Conditions: store at -20 °C

Shelf Life: 12 months

Molecular Formula: C₉H₁₆N₃O₁₄P₃ (free acid)

Molecular Weight: 483.16 g/mol (free acid)

CAS#: 36051-68-0

EC number: 252-849-3

Purity: ≥ 99 % (HPLC)

Form: clear aqueous solution

Concentration: 100 mM ±2 %

pH: 8.0 ±0.2 (22 °C)

Spectroscopic Properties: λ_max 271 nm, ε 8.9 L mmol^-1 cm^-1 (Tris-HCl pH 7.0)

Applications:
Physiological role in coronary artery disease^[1]
Physiolocal role in lipid metabolism^[2]
Physiological role in farnesol induced apoptosis^[3]

Description:
Ultrapure CTP supplied as clear aqueous solution.

Specific Ligands:

CTP synthase^[4]

Phosphocholine cytidyltransferase alpha^[2]

Ligand for purinergic receptors:
P2Y₆^[5]
P2X₃^[6]

BIOZ Product Citations:

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Selected References:
[1] Lui et al. (2010) Evaluation of CT perfusion in setting of cerebral ischemia:patterns and pitfalls. American Journal of Neuroradiology 31:1552.
[2] Luoma (2010) Gene activation regresses artheriosclerosis, promotes health, and enhances longevity. Lipids in health and disease 9:67.
[3] Joo et al. (2010) Molecular mechanisms involved in farnesol-induced apotosis. Cancer letters 287:123.
[4] Cabeen et al. (2010) A metabolic assembly line in bacteria. Nature Cell Biology 12:731.
[5]Jayasekara et al. (2013) 4-Alkoxyimino-cytosine nucleotides: tethering approaches to molecular probes for the P2Y6 receptor. MedChemComm. 4 (8):1156.
[6]Garzia-Guzman et al. (1997) Molecular characterization and pharmacological properties of the human P2X3 purinoreceptor. Mol. Brain Res. 47 (1):59.
Spangler et al. (2011) Interaction of the diguanylate cyclase YdeH of Escherichia coli with 2', (3')-substituted purine and pyrimidine nucleotides. J. Pharmacol. Exp. Ther. 336 (1):234.