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Member of Ras oncogene family

human, recombinant, E. coli

Cat. No. Amount Price (EUR) Buy / Note
PR-109 50 μg 207,00 Add to Basket/Quote Add to Notepad

For in vitro use only!

Shipping: shipped on dry ice

Storage Conditions: store at -80 °C
avoid freeze/thaw cycles

Shelf Life: 12 months

Accession number: AF498939

Accession number: AF498939

Purity: > 90 % (SDS-PAGE)

Form: liquid (Supplied in 25 mM HEPES pH 7.2, 2 mM MgCl2, 40 mM NaCl, 10 μM GDP and 3 mM DTT)

pH: 7.2

Activity: 100 pmol of protein can bind > 80 pmol of GDP.

Rab6A is a small GTPase that belongs to the Ras superfamily. It mediates intra-Golgi vesicular trafficking and is geranylgeranylated on both C-terminal cysteines.

Selected References:
Feldmann et al. (1995) Behaviour of the small GTP-binding protein rab6 in the liver of normal rats and rats presenting an acute inflammatory reaction. Biol. Cell 83:121.
Beranger et al. (1994) The effector domain of Rab6, plus a highly hydrophobic C terminus, is required for Golgi apparatus localization. Mol. Cell. Biol. 14:744.
Chamberlain et al. (2004) The p85alpha Subunit of Phosphatidylinositol 3’-Kinase Binds to and Stimulates the GTPase Activity of Rab Proteins. J. Biol. Chem. 279 (47):48607.