(iso-GTP)
2-Hydroxy-adenosine-5'-triphosphate, Sodium salt
| Cat. No. | Amount | Price (EUR) | Buy / Note |
|---|---|---|---|
| NU-1173S | 50 μl (10 mM) | 150,10 | Add to Basket/Quote Add to Notepad |
| NU-1173L | 5 x 50 μl (10 mM) | 439,50 | Add to Basket/Quote Add to Notepad |
For general laboratory use.
Shipping: shipped on gel packs
Storage Conditions: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.
Shelf Life: 12 months after date of delivery
Molecular Formula: C10H16N5O14P3 (free acid)
Molecular Weight: 523.18 g/mol (free acid)
Exact Mass: 522.99 g/mol (free acid)
Purity: ≥ 95 % (HPLC)
Form: solution in water
Color: colorless to slightly yellow
Concentration: 10 mM - 11 mM
pH: 7.5 ±0.5
Spectroscopic Properties: λmax 292 nm, ε 11.1 L mmol-1 cm-1 (Tris-HCl pH 7.5)
Applications:
Inducing C-T mutations during transcription[1]
Hydrolysis byMTH1-protein[2]
Specific Ligands:
Binding to MTH1-protein[2]
BIOZ Product Citations:
Selected References:
[1] Kamiya et al. (2007) Effects of 8-hydroxy-GTP and 2-hydroxy-ATP on in vitro transcription. Free Radical Biology and Medicine 43 (5):837.
[2] Fujikawa et al. (2001) Human MTH1 protein hydrolyzes the oxidized ribonucleotide, 2-hydroxy-ATP. Nucleic Acids Res. 29 (2):449.
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