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2-Hydroxy-ATP

(iso-GTP)

2-Hydroxy-adenosine-5'-triphosphate, Sodium salt

Cat. No. Amount Price (EUR) Buy / Note
NU-1173S 50 μl (10 mM) 126,90 Add to Basket/Quote Add to Notepad
NU-1173L 5 x 50 μl (10 mM) 371,60 Add to Basket/Quote Add to Notepad
Structural formula of 2-Hydroxy-ATP ((iso-GTP), 2-Hydroxy-adenosine-5'-triphosphate, Sodium salt)
Structural formula of 2-Hydroxy-ATP

For research use only!

Shipping: shipped on gel packs

Storage Conditions: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.

Shelf Life: 12 months after date of delivery

Molecular Formula: C10H16N5O14P3 (free acid)

Molecular Weight: 523.18 g/mol (free acid)

Exact Mass: 522.99 g/mol (free acid)

Purity: ≥ 95 % (HPLC)

Form: solution in water

Color: colorless to slightly yellow

Concentration: 10 mM - 11 mM

pH: 7.5 ±0.5

Spectroscopic Properties: λmax 292 nm, ε 11.1 L mmol-1 cm-1 (Tris-HCl pH 7.5)

Applications:
Inducing C-T mutations during transcription[1]
Hydrolysis byMTH1-protein[2]

Specific Ligands:

Binding to MTH1-protein[2]

BIOZ Product Citations:
Please click the arrow on the right to expand the citation list. Click publication title for the full text.

Selected References:
[1] Kamiya et al. (2007) Effects of 8-hydroxy-GTP and 2-hydroxy-ATP on in vitro transcription. Free Radical Biology and Medicine 43 (5):837.
[2] Fujikawa et al. (2001) Human MTH1 protein hydrolyzes the oxidized ribonucleotide, 2-hydroxy-ATP. Nucleic Acids Res. 29 (2):449.