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dTpNHpp

(dTMPNPP)

2'-Deoxythymidine-5'-[(α,β)-imido]triphosphate, Sodium salt

Cat. No. Amount Price (EUR) Buy / Note
NU-907-1 1 mg 340,30 Add to Basket/Quote Add to Notepad
Structural formula of dTpNHpp ((dTMPNPP), 2'-Deoxythymidine-5'-[(α,β)-imido]triphosphate, Sodium salt)
Structural formula of dTpNHpp

For research use only!

Shipping: shipped on blue ice

Storage Conditions: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.

Shelf Life: 12 months after date of delivery

Molecular Formula: C10H18N3O13P3 (free acid)

Molecular Weight: 481.18 g/mol (free acid)

CAS#: 141171-14-4 (free acid), 183584-80-7 (Tetrasodium salt)

Purity: ≥ 95 % (HPLC)

Form: solid

Spectroscopic Properties: λmax 267 nm, ε 9.6 L mmol-1 cm-1 (Tris-HCl pH 7.5)

Selected References:
Koag et al. (2019) Mutagenic Replication of the Major Oxidative Adenine Lesion 7,8-Dihydro-8-oxoadenine by Human DNA Polymerases. J. Am. Chem. Soc. 141 (11):4584.
Ma et al. (2008) New thymidine triphosphate analogue inhibitors of human immunodeficiency virus-1 reverse transcriptase. J. Med. Chem. 35 (11):1938.