2'-Deoxycytidine-5'-[(α,β)-methyleno]triphosphate, Sodium salt
For research use only!
Shipping: shipped on blue ice
Storage Conditions: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.
Shelf Life: 12 months after date of delivery
Molecular Formula: C10H18N3O12P3 (free acid)
Molecular Weight: 465.18 g/mol (free acid)
Exact Mass: 465.01 g/mol (free acid)
Purity: ≥ 95 % (HPLC)
Form: solution in water
Color: colorless to slightly yellow
Concentration: 10 mM - 11 mM
pH: 7.5 ±0.5
Spectroscopic Properties: λmax 271 nm, ε 9.0 L mmol-1 cm-1 (Tris-HCl pH 7.5)
Vaidyanathan et al. (2013) Insights into the Conformation of Aminofluorene-Deoxyguanine Adduct in a DNA Polymerase Active Site J. Biol. Chem. 288 (32):23573–23585.
Liang et al. (2008) Alpha,beta-methylene-2'-deoxynucleoside 5'-triphosphates as noncleavable substrates for DNA polymerases: isolation, characterization, and stability studies of novel 2'-deoxycyclonucleosides, 3,5'-cyclo-dG, and 2,5'-cyclo-dT. J. Med. Chem. 51 (20):6460-70.