6-Methylthio-GTP
For research use only.
Please centrifuge briefly before opening (volume ≤2 ml).
Shipping: shipped on gel packs
Storage Conditions: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.
Shelf Life: 12 months after date of delivery
Molecular Formula: C11H18N5O13P3S (free acid)
Molecular Weight: 553.27 g/mol (free acid)
Exact Mass: 552.98 g/mol (free acid)
CAS#: 70318-62-6
Purity: ≥ 95 % (HPLC)
Form: solution in water
Color: colorless to slightly yellow
Concentration: 10 mM - 11 mM
pH: 7.5 ±0.5
Spectroscopic Properties: λmax 242 nm, ε 12.8 L mmol-1 cm-1 (Tris-HCl pH 7.5)
Selected References:
Labesse et al. (2011) Structural and functional characterization of the Mycobacterium tuberculosis uridine monophosphate kinase: insights into the allosteric regulation. Nucleic Acids Res. 39 (8):3458.
Nelson et al. (1977) Oxypurine and 6-thiopurine nucleoside triphosphate formation in human erythrocytes. Adv. Exp. Med. Biol. 76A:121.
| Cat. No. | Amount | Price |
|---|---|---|
| NU-1130S | 100 μl (10 mM) | 157,60 € |
| NU-1130L | 5 x 100 μl (10 mM) | 461,30 € |
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Scientific citations for Jena Bioscience nu-1130
3 scientific citations and 0 citation images found by Bioz.
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Development of a Simple In Vitro Assay To Identify and Evaluate Nucleotide Analogs against SARS-CoV-2 RNA-Dependent RNA Polymerase
Antimicrobial Agents and Chemotherapy, 2020-12-16 · DOI:10.1128/aac.01508-20
.. (San Diego, CA).Tenofovir-DP, 2’-C-methyl-CTP, and 2’-C-methyl-GTP were purchased 100 from Carbosynth (San Diego, CA).. 6-chloropurine-TP, gemcitabine-TP,
6-methyl-thio-GTP , 101 clofarabine-TP, 8-Oxo-GTP, 6-Thio-GTP, stavudine-TP, and lamivudine-TP were purchased 102 fromJena Bioscience (Jena, Germany).. Ribavirin-TP was purchased from Santa Cruz 103 Biotechnology (Texas, USA).Ribavirin-TP was purchased from Santa .. -
Discovery of five HIV nucleoside analog reverse-transcriptase inhibitors (NRTIs) as potent inhibitors against the RNA-dependent RNA polymerase (RdRp) of SARS-CoV and 2019-nCoV
bioRxiv, 2020-11-01 · DOI:10.1101/2020.11.01.363788
PrePrint: 6-Mercaptopurine-TP (NU-1110S), 6-chloropurine-TP (NU-1109S), clofarabine-TP (NU-874),
6-methylthio-GTP (NU-1130S), 6-thio-GTP (NU-1106S), stavudine-TP (NU-1604S), 8-oxo-GTP (NU-1116S), gemcitabine-TP (NU-1607S), acyclovir-TP (NU-877), ganciclovir-TP (NU-275S), lamivudine-TP (NU-1606L) and zidovudine-TP (NU-989S) were purchased fromJena Bioscience . -
Structural and functional characterization of the Mycobacterium tuberculosis uridine monophosphate kinase: insights into the allosteric regulation
Nucleic Acids Research, 2011-04-01 · PMID:21149268
.. were purchased from Sigma.ATP, GTP, UTP, dUTP, dGTP and dTTP were purchased from Sigma.. 5F-UMP, 5Br-UMP, 5F-UTP, 5I-UTP, aminoallyl UTP, 8Br-GTP, Mant-GTP,
6-methylthio GTP , GMPPCP and GMPPNP were purchased fromJena Bioscience .. NDP kinase was kindly provided by I. Lascu.NDP kinase was kindly provided by I. ..
