GTP - Solution
For research use only.
Please centrifuge briefly before opening (volume ≤2 ml).
Description:
Ultrapure GTP supplied as clear aqueous solution.
Shipping: shipped on gel packs
Storage Conditions: store at -20 °C
Shelf Life: 12 months
Molecular Formula: C10H16N5O14P3 (free acid)
Molecular Weight: 523.18 g/mol (free acid)
CAS#: 36051-31-7
Purity: ≥ 99 % (HPLC)
Form: clear aqueous solution
Concentration: 100 mM ±2 %
pH: 8.0 ±0.2 (22 °C)
Spectroscopic Properties: λmax 252 nm, ε 14.2 L mmol-1 cm-1 (Tris-HCl pH 7.0)
Applications:
Assembly of ribosomal units[1]
Microdomain formation by small GTPases[2]
Antiviral activity of large GTPases (dynamin superfamily)[3]
Regulation of exocytosis by Rho GTPases[4]
Mechanism of hydrolysis by ADP-ribosylation factors[5]
Specific Ligands:
Guanylate binding proteins[6]
Yeast septins[7]
Selected References:
[1] Blombach et al. (2011) Assembling the archeal ribosome: roles for transition factor-related GTPases. Biochemical Society Transactions 39:45.
[2] Stuermer (2011) Microdomain-forming proteins and the role of the reggies/flottilins during axon regeneration in zebrafish. Biochimica Biophysica Acta, Molecular Basis of Disease 1812:415.
[3] Haller et al. (2011) Human MxA protein: An Interferon-induced Dynamin-like GTPase with broad antiviral activity. J. Interferon and Cytokine Research 31:79.
[4] Stephane et al. (2011) Rho GTPases and exocytosis: what are the molecular links? Seminars in Cell and Developmental Biology 22:27.
[5] East et al. (2011) Models for the function of Arf GAPs. Seminars in Cell and Developmentan Biology 22:3.
[6] Vestal et al. (2011) The guanylate binding proteins: Emerging insights into the biochemical properties and functions of this family of large interferon-induced guanosine triphosphatase. J. Interferon and Cytokine Research 31:89.
[7] Younghoon et al. (2011) Septin structure and function in yeast and beyond. Trends in Cell Biology 21:141.
Drummond et al. (2011) Reconstitution and Organization of Escherichia coli Proto-ring Elements (FtsZ and FtsA) inside Giant Unilamellar Vesicles Obtained from Bacterial Inner Membranes. Methods Mol. Biol. 777 :29.
Katsuki et al. (2011) Preparation of dual-color polarity-marked fluorescent microtubule seeds. Methods Mol. Biol. 777:117.
Ramachandran et al. (2009) Membrane Insertion of the Pleckstrin Homology Domain Variable Loop 1 Is Critical for Dynamin-catalyzed Vesicle Scission. Molecular Biology of the Cell 20 (22):4630.
| Cat. No. | Amount | Price |
|---|---|---|
| NU-1012 | 1 ml (100 mM) | 52,30 € |
| NU-1012-100ML | 100 ml (100 mM) | Ask for Quotation |
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Scientific citations for Jena Bioscience nu-1012-sol
65 scientific citations and 23 citation images found by Bioz.
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Recoding by N 1 -methylpseudouridine guides rational mRNA vaccine design
Nature Communications, 2026-09-28 · PMID:42805987
.. NHS ester (Cytiva, PA15101) was carried out as described .. To form the IC(L11-Cy3), 70S(L11-Cy3) (1 μM) were mixed with IF1, IF2, IF3 (3 μM), GTP (1 mM, Jena Bioscience,
NU-1012 -
Taxane-induced conformational changes in the microtubule lattice activate GEF-H1-dependent RhoA signalling.
Nature cell biology, 2026-09-24 · PMID:42786275
.. T333P) was diluted 1:50 with unlabelled porcine brain tubulin to obtain biotin-labelled tubulin mix.. Twelve protofilament microtubules were polymerized from 4 mg ml−1 of biotin-labelled tubulin for 1 h at 37 °C in 10 mM phosphate buffer supplemented with 6 mM MgCl2, 2 μM paclitaxel and 1 mM GTP (
NU-1012 Jena Bioscience ), according to ref. 93.. Polymerized microtubules were centrifuged for 30 min at 18,000g in a Microfuge 18 centrifuge .. -
Surface-induced tau condensation generates a selective microenvironment around microtubules
bioRxiv, 2026-08-20 · DOI:10.64898/2026.08.20.745963
PrePrint: .. resuspended in BRB80, stored at room temperature and used within one week of preparation.. GDP microtubules (stabilized with GMPCPP caps) were polymerized from 4 mg/mL tubulin (1:50 biotin-labeled to unlabeled tubulin) in BRB80 supplemented with 4 mM MgCl 2 , 1 mM GTP (
Jena Bioscience ,NU-1012
