» Sign in / Register


Ras-associated, small GTP-binding protein

rat, recombinant, E. coli

Cat. No. Amount Price (EUR) Buy / Note
PR-187 50 μg 207,00 Add to Basket/Quote Add to Notepad

For in vitro use only!

Shipping: shipped on dry ice

Storage Conditions: store at -80 °C
avoid freeze/thaw cycles

Shelf Life: 12 months

Accession number: NP_446041

Accession number: NP_446041

Purity: > 90 % (SDS-PAGE)

Form: liquid (Supplied in 50 mM Tris-HCl pH 8.0, 100 mM NaCl, 10 mM MgCl2, 10 μM GDP and 2 mM mercaptoethanol)

pH: 8.0

Activity: 100 pmol of protein can bind > 80 pmol of GDP.

Rab14 is a small GTPase that belongs to the Ras superfamily. Rab proteins play an important role in various aspects of membrane traffic, including cargo selection, vesicle budding, vesicle motility, tethering, docking, and fusion. Rab14 is involved in phagosome and early endosome fusion.It also plays an important role in trafficking between early endosomes and Golgi.Therefore it is located in the rough ER, Golgi/trans-Golgi and early endosomes.

Selected References:
Stenmark et al. (2001) The Rab GTPase family. Genome Biol. 2:30071.
Yamaguchi et al. (2002) A GDP/GTP exchange protein for the Rab3 small G protein family up-regulates a postdocking step of synaptic exocytosis in central synapses. Proc. Natl. Acad. Sci. USA. 99:14536.