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REP-2His

Rab Escort Protein

human, recombinant, Saccharomyces cerevisiae

Product Cat. No. Amount Price (EUR) Buy / Note
REP-2His PR-104 50 μg 207,00 Add to Basket/Quote Add to Notepad

For in vitro use only!

Shipping: shipped on dry ice

Storage Conditions: store at -80 °C
avoid freeze/thaw cycles

Shelf Life: 12 months

Accession number: NM_001821

Accession number: NM_001821

Purity: > 90 % (SDS-PAGE)

Form: liquid (Supplied in 25 mM HEPES pH 7.2, 40 mM NaCl and 5 mM DTT)

pH: 7.2

Activity: 1 pmol of REP-2 will mediate transfer of 2 pmol of geranylgeraniol by RabGGTase onto 1 pmol of Rab7 in 3 minutes.

Description:
C-terminal His-tagged REP-2 (Rab escort protein-2) binds to a wide range of RabGGTase with nanomolar affinities and supports the prenylation of RabGTPase mediated by RabGGTase, with an exception of Rab27.

Selected References:
Cremers et al. (1994) REP-2, a Rab escort protein encoded by the choroideremia-like gene. J. Biol. Chem. 269:2111.