Rab Escort Protein
human, recombinant, Saccharomyces cerevisiae
For in vitro use only!
Shipping: shipped on dry ice
Storage Conditions: store at -80 °C
avoid freeze/thaw cycles
Shelf Life: 12 months
Accession number: NM_001821
Purity: > 90 % (SDS-PAGE)
Form: liquid (Supplied in 25 mM HEPES pH 7.2, 40 mM NaCl and 10 mM DTT)
Activity: 1 pmol of REP-2 will mediate transfer of 2 pmol of geranylgeraniol by RabGGTase onto 1 pmol of Rab7 in 3 minutes.
C-terminal His-tagged REP-2 (Rab escort protein-2) binds to a wide range of RabGGTase with nanomolar affinities and supports the prenylation of RabGTPase mediated by RabGGTase, with an exception of Rab27.
BIOZ Product Citations:
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Cremers et al. (1994) REP-2, a Rab escort protein encoded by the choroideremia-like gene. J. Biol. Chem. 269:2111.