2'/3'-O-(N-Methyl-anthraniloyl)-xanthosine-5'-triphosphate, Triethylammonium salt
For research use only!
Shipping: shipped on blue ice
Storage Conditions: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.
Shelf Life: 12 months after date of delivery
Molecular Formula: C18H22N5O16P3 (free acid)
Molecular Weight: 657.31 g/mol (free acid)
Purity: ≥ 95 % (HPLC)
Form: colorless to slightly yellow solution in water
Concentration: 10 mM - 11 mM
pH: 7.5 ±0.5
Spectroscopic Properties: λmax 254/355 nm, ε 19.0/5.8 L mmol-1 cm-1 (Tris-HCl pH 7.5), λexc 355 nm, λem 448 nm
Pinto et al. (2011) Structure-activity relationships for the interactions of 2'- and 3'- (O)- (N-methyl)anthraniloyl-substituted purine and pyrimidine nucleotides with mammalian adenylyl cyclases. Biochem. Pharmacol. 82 (4):358.
Spangler et al. (2011) Interaction of the diguanylate cyclase YdeH of Escherichia coli with 2', (3')-substituted purine and pyrimidine nucleotides. J. Pharmacol. Exp. Ther. 336 (1):234.
Tung-Chung Mou et al. (2005) Structural Basis for the Inhibition of Mammalian Membrane Adenylyl Cyclase by 2' (3')-O- (N-Methylanthraniloyl)- guanosine 5'-Triphosphate. J. Biol. Chem. 280 (8) :7253.
Gille et al. (2004) Xanthine nucleotide-specific G-protein α-subunits: a novel approach for the analysis of G-protein-mediated signal transduction. Naunyn-Schmiedeberg's Arch. Pharmacol. 369 :141.
Aronsson et al. (2003) Unusual nucleotide-binding properties of the chloroplast protein import receptor, atToc33.FEBS Letters 544 :79.