Gemcitabine-5'-monophosphate

For general laboratory use.

Shipping: shipped on gel packs

Storage Conditions: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.

Shelf Life: 12 months after date of delivery

Molecular Formula: C₉H₁₂F₂N₃O₇P (free acid)

Molecular Weight: 343.18 g/mol (free acid)

Exact Mass: 343.04 g/mol (free acid)

CAS#: 116371-67-6

Purity: ≥ 95 % (HPLC)

Form: solid

Color: white to off-white

Spectroscopic Properties: λ_abs 271 nm, ε 9.1 L mmol^-1 cm^-1 (Tris-HCl pH 7.5)

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Selected References:
Aksoy et al. (2009) Cytosolic 5'-nucleotidase III (NT5C3): gene sequence variation and functional genomics. Pharmacogenet Genomics 19 (8):567.
Veltkamp et al. (2008) New insights into the pharmacology and cytotoxicity of gemcitabine and 2',2'-difluorodeoxyuridine. Mol Cancer Ther 7 (8):2415.
Kocabas et al. (2008) Gemcitabine pharmacogenomics: deoxycytidine kinase and cytidylate kinase gene resequencing and functional genomics. Drug Metab Dispos 36 (9):1951.