Acyclovir-5'-triphosphate

For general laboratory use.

Shipping: shipped on gel packs

Storage Conditions: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.

Shelf Life: 12 months after date of delivery

Molecular Formula: C₈H₁₄N₅O₁₂P₃ (free acid)

Molecular Weight: 465.14 g/mol (free acid)

Exact Mass: 464.99 g/mol (free acid)

CAS#: 66341-18-2

Purity: ≥ 95 % (HPLC)

Form: solid

Color: clear to slightly yellow

Spectroscopic Properties: λ_max 252 nm, ε 13.7 L mmol^-1 cm^-1 (Tris-HCl pH 7.5)

BIOZ Product Citations:

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Selected References:
Keller et al. (2008) Interaction of Herpes Primase with the Sugar of a NTP. Biochemistry 47 (34):8977.
Hanes et al. (2007) Enzymatic Therapeutic Index of Acyclovir: Viral versus human polymerase γ specificity. Journal of Biological Chemistry 282 (34):25159.
Huang et al. (1999) The enzymological basis for resistance of herpesvirus DNA polymerase mutants to acyclovir: relationship to the structure of α -like DNA polymerases. Proceedings of the National Academy of Sciences of the United States of America 96 (2):447.