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Ganciclovir-triphosphate

Sodium salt

GCV-TP

9-(1,3-Dihydroxy-2-propoxymethyl)guanine-5'-triphosphate

Cat. No. Amount Price (EUR) Buy / Note
NU-275S 10 μl (100 mM)275,30 Add to Basket/Quote Add to Notepad
NU-275L 5 x 10 μl (100 mM)1.101,00 Add to Basket/Quote Add to Notepad
Structural formula of Ganciclovir-triphosphate (Sodium salt, 9-(1,3-Dihydroxy-2-propoxymethyl)guanine-5'-triphosphate)
Structural formula of Ganciclovir-triphosphate

For general laboratory use.

Shipping: shipped on gel packs

Storage Conditions: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.

Shelf Life: 12 months after date of delivery

Molecular Formula: C9H16N5O13P3 (free acid)

Molecular Weight: 495.17 g/mol (free acid)

Exact Mass: 495.00 g/mol (free acid)

Purity: ≥ 95 % (HPLC)

Form: solution in water

Color: colorless to slightly yellow

Concentration: 100 mM - 110 mM

pH: 7.5 ±0.5

Spectroscopic Properties: λmax 252 nm, ε 13.6 L mmol-1 cm-1 (Tris-HCl pH 7.5)

BIOZ Product Citations:

Selected References:
Davis et al. (2007) Hypoxia Enhances the Phosphorylation and Cytotoxicity of Ganciclovir and Zidovudine in Kaposi's Sarcoma-Associated Herpesvirus–Infected Cells. Cancer Res. 67:7003.
Zhu et al. (2005) Potent Antiviral Activity of North-Methanocarbathymidine against Kaposi's Sarcoma-Associated Herpesvirus. Antimicrob. Agents Chemother. 49:4965.
Rubsam et al. (1999) Cytotoxicity and accumulation of ganciclovir triphosphate in bystander cells cocultured with herpes simplex virus type 1 thymidine kinase-expressing human glioblastoma cells. Cancer Res. 59:669.