Ganciclovir-triphosphate
For general laboratory use.
Please centrifuge briefly before opening (volume ≤2 ml).
Shipping: shipped on gel packs
Storage Conditions: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.
Shelf Life: 12 months after date of delivery
Molecular Formula: C9H16N5O13P3 (free acid)
Molecular Weight: 495.17 g/mol (free acid)
Exact Mass: 495.00 g/mol (free acid)
Purity: ≥ 95 % (HPLC)
Form: solution in water
Color: colorless to slightly yellow
Concentration: 100 mM - 110 mM
pH: 7.5 ±0.5
Spectroscopic Properties: λmax 252 nm, ε 13.6 L mmol-1 cm-1 (Tris-HCl pH 7.5)
Selected References:
Davis et al. (2007) Hypoxia Enhances the Phosphorylation and Cytotoxicity of Ganciclovir and Zidovudine in Kaposi's Sarcoma-Associated Herpesvirus–Infected Cells. Cancer Res. 67:7003.
Zhu et al. (2005) Potent Antiviral Activity of North-Methanocarbathymidine against Kaposi's Sarcoma-Associated Herpesvirus. Antimicrob. Agents Chemother. 49:4965.
Rubsam et al. (1999) Cytotoxicity and accumulation of ganciclovir triphosphate in bystander cells cocultured with herpes simplex virus type 1 thymidine kinase-expressing human glioblastoma cells. Cancer Res. 59:669.
| Cat. No. | Amount | Price |
|---|---|---|
| NU-275S | 10 μl (100 mM) | 288,90 € |
| NU-275L | 5 x 10 μl (100 mM) | 1.155,50 € |
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