Dibenzocyclooctyne (DBCO)*-containing (desthio) biotinylation reagents can be used for the labeling of Azide-tagged biomolecules via Cu(I)-free strain-promoted Alkyne-Azide Click Chemistry (SPAAC).
A number of (desthio) biotinylation reagents with
are available to fit specific application & molecule requirements.
- different solubility characteristics (PEG- and Sulfo-linker for increased molecule solubility)
- different cleavability characteristics (chemically or photocleavable linke)
DBCO is also known as ADIBO (= Azadibenzocyclooctyne) or DIBAC (= Dibenzoazacyclooctyne)