Dibenzocyclooctyne (DBCO)*-containing bifunctional reagents can be used for the introduction of
- a functional group to Azide-labeled molecules via Cu(I)-free strain-promoted Alkyne-Azide Click Chemistry (SPAAC)
- an DBCO group to various targets e.g. via NHS Ester- or Maleimide-based chemistry
*DBCO is also known as ADIBO (= Azadibenzocyclooctyne) or DIBAC (= Dibenzoazacyclooctyne)