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5-Iodo-UDP

(5I-UDP)

5-Iodo-uridine-5'-diphosphate, Sodium salt

Cat. No. Amount Price (EUR) Buy / Note
NU-867S 50 μl (10 mM) 117,35 Add to Basket/Quote Add to Notepad
NU-867L 5 x 50 μl (10 mM) 343,76 Add to Basket/Quote Add to Notepad
Structural formula of 5-Iodo-UDP ((5I-UDP), 5-Iodo-uridine-5'-diphosphate, Sodium salt)
Structural formula of 5-Iodo-UDP

For research use only!

Shipping: shipped on blue ice

Storage Conditions: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.

Shelf Life: 12 months after date of delivery

Molecular Formula: C9H13N2O12P2I (free acid)

Molecular Weight: 530.06 g/mol (free acid)

Exact Mass: 529.90 g/mol (free acid)

CAS#: 34198-43-1

Purity: ≥ 95 % (HPLC)

Form: clear aqueous solution

Concentration: 10 mM - 11 mM

pH: 7.5 ±0.5

Spectroscopic Properties: λmax 287 nm, ε 7.7 L mmol-1 cm-1 (Tris-HCl pH 7.5)

Specific Ligands:

Selective agonistic ligand for P2Y6 receptor[1,2,3]

Selected References:
[1] Besada et al. (2006) Structure-activity relationships of uridine-5'-diphosphate analogues at the human P2Y6 receptor. J. Med. Chem. 49 (18):5532.
[2] Mamedova et al. (2008) Attenuation of apoptosis in vitro and ischemia/reperfusion injury in vivo in mouse skeletal muscle by P2Y6 receptor activation. Pharmacol. Res. 58 (3-4):232.
[3] Jacobson et al. (2009) Development of selective agonists and antagonists of P2Y receptors. Purinergic Signalling 5:75.

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