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5-Bromo-UMP

(5Br-UMP)

5-Bromo-uridine-5'-monophosphate, Sodium salt

Cat. No. Amount Price (EUR) Buy / Note
NU-135S 100 μl (10 mM) 117,35 Add to Basket/Quote Add to Notepad
NU-135L 5 x 100 μl (10 mM) 343,76 Add to Basket/Quote Add to Notepad
Structural formula of 5-Bromo-UMP ((5Br-UMP), 5-Bromo-uridine-5'-monophosphate, Sodium salt)
Structural formula of 5-Bromo-UMP

For research use only!

Shipping: shipped on blue ice

Storage Conditions: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.

Shelf Life: 12 months after date of delivery

Molecular Formula: C9H12BrN2O9P (free acid)

Molecular Weight: 403.08 g/mol (free acid)

Exact Mass: 401.95 g/mol (free acid)

CAS#: 2149-79-3

Purity: ≥ 95 % (HPLC)

Form: clear aqueous solution

Concentration: 10 mM - 11 mM

pH: 7.5 ±0.5

Spectroscopic Properties: λmax 278 nm, ε 9.7 L mmol-1 cm-1 (Tris-HCl pH 7.5)

Selected References:
Labesse et al. (2011) Structural and functional characterization of the Mycobacterium tuberculosis uridine monophosphate kinase: insights into the allosteric regulation. Nucleic Acids Res. 39 (8):3458.
Gilles et al. (2007) Regulatory Mechanisms Differ in UMP Kinases from Gram-negative and Gram-positive Bacteria. J. Biol. Chem. 282 (10):7242.
Kwon et al. (1999) Bipartite modular structure of intrinsic, RNA hairpin-independent termination signal for phage RNA polymerases. J. Biol. Chem. 274 (41):29149.
Tourneux et al. (1998 ) Substitution of an alanine residue for glycine 146 in TMP kinase from Escherichia coli is responsible for bacterial hypersensitivity to bromodeoxyuridine. J. Bacteriol. 180 (16):4291.