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m7GMP-α-F

(m7GpF)

7-Methyl-guanosine-5'-(α-fluoro)-monophosphate

7-Methyl-guanosine-5'-(1-fluoro)-monophosphate

Cat. No. Amount Price (EUR) Buy / Note
NU-944-5 5 mg 105,08 Add to Basket/Quote Add to Notepad
NU-944-25 25 mg 420,31 Add to Basket/Quote Add to Notepad
Structural formula of m7GMP-α-F ((m7GpF), 7-Methyl-guanosine-5'-(α-fluoro)-monophosphate)
Structural formula of m7GMP-α-F

For in vitro use only!

Shipping: shipped on blue ice

Storage Conditions: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.

Shelf Life: 12 months after date of delivery

Molecular Formula: C11H15FN5O7P

Molecular Weight: 379.24 g/mol

Exact Mass: 379.07 g/mol

CAS#: 1698011-01-6 (inner salt)

Purity: ≥ 95 % (HPLC)

Form: solid

Spectroscopic Properties: λmax 258/280 nm, ε 9.8/8.0 L mmol-1 cm-1 (Tris-HCl pH 7.5)

Applications:
Substrate for human mRNA decapping scavenger enzyme [1,2]

Selected References:
[1] Baranowski et al. (2016) A fluorescent HTS assay for phosphohydrolases based on nucleoside 5'-fluorophosphates: its application in screening for inhibitors of mRNA decapping scavenger and PDE-I. Org. Biomol. Chem. 14 (20):4595.
[2] Baranowski et al. (2015) Synthesis of fluorophosphate nucleotide analogues and their characterization as tools for ¹⁹F NMR studies. J. Org. Chem. 80 (8):3982.