(ApF)
Adenosine-5'-(α-fluoro)-monophosphate, Sodium salt
Adenosine-5'-(1-fluoro)-monophosphate, Sodium salt
| Cat. No. | Amount | Price (EUR) | Buy / Note |
|---|---|---|---|
| NU-943-5 | 5 mg | 134,30 | Add to Basket/Quote Add to Notepad |
| NU-943-25 | 25 mg | 537,40 | Add to Basket/Quote Add to Notepad |
For general laboratory use.
Shipping: shipped on gel packs
Storage Conditions: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.
Shelf Life: 12 months after date of delivery
Molecular Formula: C10H13FN5O6P (free acid)
Molecular Weight: 349.21 g/mol (free acid)
Exact Mass: 349.06 g/mol (free acid)
CAS#: 19375-33-8 (free acid), 15503-75-0 (sodium salt)
Purity: ≥ 95 % (HPLC)
Form: solid
Color: white to off-white
Spectroscopic Properties: λmax 259 nm, ε 15.4 L mmol-1 cm-1 (Tris-HCl pH 7.5)
Applications:
Substrate for snake venom phosphodiesterase [1,2]
Substrate for Fhit proteins [3]
Inhibitor of adenlyate kinase [4]
BIOZ Product Citations:
Selected References:
[1] Baranowski et al. (2016) A fluorescent HTS assay for phosphohydrolases based on nucleoside 5'-fluorophosphates: its application in screening for inhibitors of mRNA decapping scavenger and PDE-I. Org. Biomol. Chem. 14 (20):4595.
[2] Baranowski et al. (2015) Synthesis of fluorophosphate nucleotide analogues and their characterization as tools for ¹⁹F NMR studies. J. Org. Chem. 80 (8):3982.
[3] Guranowski et al. (2008) Fhit proteins can also recognize substrates other than dinucleoside polyphosphates. FEBS Lett. 582 (20):3152.
[4] Scoblov et al. (1996) Modified nucleotides as substrates and inhibitors of adenylate kinase from different sources. FEBS Lett. 395 (2-3):283.
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