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Adenosine-2',5'-bisphosphate

Adenosine-2',5'-bisphosphate, Sodium salt

Cat. No. Amount Price (EUR) Buy / Note
NU-1113S 100 μl (10 mM) 114,49 Add to Basket/Quote Add to Notepad
NU-1113L 5 x 100 μl (10 mM) 335,38 Add to Basket/Quote Add to Notepad
Structural formula of Adenosine-2',5'-bisphosphate (Adenosine-2',5'-bisphosphate, Sodium salt)
Structural formula of Adenosine-2',5'-bisphosphate

For research use only!

Shipping: shipped on blue ice

Storage Conditions: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.

Shelf Life: 12 months after date of delivery

Molecular Formula: C10H15N5O10P2 (free acid)

Molecular Weight: 427.20 g/mol (free acid)

CAS#: 3805-37-6

Purity: ≥ 95 % (HPLC)

Form: clear aqueous solution

Concentration: 10 mM - 11 mM

pH: 7.5 ±0.5

Spectroscopic Properties: λmax 259 nm, ε 15.3 L mmol-1 cm-1 (Tris-HCl pH 7.5)

Selected References:
Bierau et al. (2007) Pharmacogenetic significance of inosine triphosphatase. Pharmacogenomics 8 (9):1221.
Toth-Zsamboki et al. (2001) The P2Y (1) receptor antagonist adenosine-2 ',5 '-diphosphate non-selectively antagonizes the platelet P2X (1) ion channel. Thromb. Haemostasis 86 (5):1338.
Leonidas et al. (2001) Mapping the ribonucleolytic active site of eosinophil-derived neurotoxin (EDN) - High resolution crystal structures of EDN complexes with adenylic nucleotide inhibitors. J. Biol. Chem. 276 (18):15009.
Gu et al. (2000) Crystal structures of the complexes of trichosanthin with four substrate analogs and catalytic mechanism of RNA N-glycosidase. Proteins 39 (1):37.
Muruganandam et al. (1994) Isolation of nitric-oxide synthase from human platelets. BBA-Gen. Subjects 1200 (1):1.
Forstermann et al. (1991) Calmodulin-dependent endothelium-derived relaxing factor nitric-oxide synthase activity is present in the particulate and cytosolic fractions of bovine aortic endothelial-cells. P. Natl. Acad. Sci. USA 88 (5):1788.
Schmidt et al. (1991) Purification of a soluble isoform of guanylyl cyclase-activating-factor synthase. P. Natl. Acad. Sci. USA 88 (2):365.
Buitrago et al. (1986) Occurrence of Adenosine 2',5'-bisphosphate in rat-liver. Biochim. Biophys. Acta 881 (2):276.
Johnston et al. (1980) Interferon-induced (2'-5')oligoadenylate synthetase - adsorption to and assay on Adenosine 2',5'- diphosphate-sepharose. Biochemistry-US 19 (24):5580.
Chung et al. (1978) Conformation of Adenosine 2',5'-diphosphate and Adenosine 3',5'-diphosphate. J. Carb.-Nucleos.-Nucl. 5 (6):469.
Hojeberg et al. (1976) Affinity chromatography and binding studies on immobilized Adenosine 5'-monophosphate and Adenosine 2',5'-bisphosphate of nicotinamide nucleotide transhydrogenase from Pseudomonas-aeruginosa. Eur. J. Biochem. 66 (3):467.