N3-Phenacyl-uridine-5'-diphosphate, Sodium salt
For research use only!
Shipping: shipped on blue ice
Storage Conditions: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.
Shelf Life: 12 months after date of delivery
Molecular Formula: C17H20N2O13P2 (free acid)
Molecular Weight: 522.29 g/mol (free acid)
Exact Mass: 522.04 g/mol (free acid)
Purity: ≥ 95 % (HPLC)
Form: clear aqueous solution
Concentration: 10 mM - 11 mM
pH: 7.5 ±0.5
Spectroscopic Properties: λmax 249 nm, ε 16.3 L mmol-1 cm-1 (Tris-HCl pH 7.5)
Ligand for purinergic receptors:
Potent and selective agonist at P2Y6 receptors[1,2]
 Mitchell et al. (2012) Identification of contractile P2Y1, P2Y6, and P2Y12 receptors in the pulmonary artery using selective ligands. J. Pharmacol. Exp. Ther. 343 (3):755.
 El-Tayeb et al. (2006) Synthesis and structure-activity relationships of uracil nucleotide derivatives and analogues as agonists at human P2Y2, P2Y4, and P2Y6 receptors. J. Med. Chem. 49 (24):7076.