5'-Aminoimidazole-4-carboxamide-1-β-D-ribofuranosyl-5'-diphosphate, Sodium salt
For research use only!
Shipping: shipped on gel packs
Storage Conditions: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.
Shelf Life: 12 months after date of delivery
Molecular Formula: C9H16N4O11P2 (free acid)
Molecular Weight: 418.19 g/mol (free acid)
Exact Mass: 418.03 g/mol (free acid)
Purity: ≥ 95 % (HPLC)
Form: solution in water
Color: colorless to slightly yellow
Concentration: 10 mM - 11 mM
pH: 7.5 ±0.5
Spectroscopic Properties: λmax 265 nm, ε 12.5 L mmol-1 cm-1 (Tris-HCl pH 7.5)
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Corton et al. (1995) 5-Aminoimidazole-4-carboxamide ribonucleoside: a specific method for activating protein kinase in intact cells? Eur J Biochem. 229:558.
Henin et al. (1995) Inhibition of fatty acid and cholesterol synthesis by stimulation of AMP-activated protein kinase. FASEB J. 9:54.
Henin et al. (1996) Stimulation of rat liver AMP-activated protein kinase by AMP analogues. Biochim Biophys Acta. 1290:197.
Sullivan et al. (1994) Inhibition of lipolysis and lipogenesis in isolated rat adipocytes with AICAR, a cell-permeable activator of AMP-activated protein kinase. FEBS Lett. 353:33.