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ZTP

(AICAR triphosphate)

5'-Aminoimidazole-4-carboxamide-1-β-D-ribofuranosyl-5'-triphosphate, Sodium salt

Cat. No. Amount Price (EUR) Buy / Note
NU-1166S 50 μl (10 mM) 114,49 Add to Basket/Quote Add to Notepad
NU-1166L 5 x 50 μl (10 mM) 335,38 Add to Basket/Quote Add to Notepad
Structural formula of ZTP ((AICAR triphosphate), 5'-Aminoimidazole-4-carboxamide-1-β-D-ribofuranosyl-5'-triphosphate, Sodium salt)
Structural formula of ZTP

For research use only!

Shipping: shipped on blue ice

Storage Conditions: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.

Shelf Life: 12 months after date of delivery

Molecular Formula: C9H17N4O14P3 (free acid)

Molecular Weight: 498.17 g/mol (free acid)

Purity: ≥ 95 % (HPLC)

Form: clear aqueous solution

Concentration: 10 mM - 11 mM

pH: 7.5 ±0.5

Spectroscopic Properties: λmax 265 nm, ε 12.5 L mmol-1 cm-1 (Tris-HCl pH 7.5)

Selected References:
Corton et al. (1995) 5-Aminoimidazole-4-carboxamide ribonucleoside: a specific method for activating protein kinase in intact cells? Eur J Biochem. 229:558.
Henin et al. (1995) Inhibition of fatty acid and cholesterol synthesis by stimulation of AMP-activated protein kinase. FASEB J. 9:54.
Henin et al. (1996) Stimulation of rat liver AMP-activated protein kinase by AMP analogues. Biochim Biophys Acta. 1290:197.
Sullivan et al. (1994) Inhibition of lipolysis and lipogenesis in isolated rat adipocytes with AICAR, a cell-permeable activator of AMP-activated protein kinase. FEBS Lett. 353:33.