(AICAR triphosphate)
5'-Aminoimidazole-4-carboxamide-1-β-D-ribofuranosyl-5'-triphosphate, Sodium salt
| Cat. No. | Amount | Price (EUR) | Buy / Note |
|---|---|---|---|
| NU-1166S | 50 μl (10 mM) | 150,10 | Add to Basket/Quote Add to Notepad |
| NU-1166L | 5 x 50 μl (10 mM) | 439,50 | Add to Basket/Quote Add to Notepad |
For general laboratory use.
Shipping: shipped on gel packs
Storage Conditions: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.
Shelf Life: 12 months after date of delivery
Molecular Formula: C9H17N4O14P3 (free acid)
Molecular Weight: 498.17 g/mol (free acid)
Exact Mass: 498.00 g/mol (free acid)
Purity: ≥ 95 % (HPLC)
Form: solution in water
Color: colorless to slightly yellow
Concentration: 10 mM - 11 mM
pH: 7.5 ±0.5
Spectroscopic Properties: λmax 265 nm, ε 12.5 L mmol-1 cm-1 (Tris-HCl pH 7.5)
Selected References:
Corton et al. (1995) 5-Aminoimidazole-4-carboxamide ribonucleoside: a specific method for activating protein kinase in intact cells? Eur J Biochem. 229:558.
Henin et al. (1995) Inhibition of fatty acid and cholesterol synthesis by stimulation of AMP-activated protein kinase. FASEB J. 9:54.
Henin et al. (1996) Stimulation of rat liver AMP-activated protein kinase by AMP analogues. Biochim Biophys Acta. 1290:197.
Sullivan et al. (1994) Inhibition of lipolysis and lipogenesis in isolated rat adipocytes with AICAR, a cell-permeable activator of AMP-activated protein kinase. FEBS Lett. 353:33.
