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2'-Deoxyuridine-5'-[(α,β)-imido]diphosphate, Sodium salt

Cat. No. Amount Price (EUR) Buy / Note
NU-902S 100 μl (10 mM)157,60 Add to Basket/Quote Add to Notepad
NU-902L 5 x 100 μl (10 mM)461,70 Add to Basket/Quote Add to Notepad
Structural formula of dUpNHp ((dUMPNP), 2'-Deoxyuridine-5'-[(α,β)-imido]diphosphate, Sodium salt)
Structural formula of dUpNHp

For general laboratory use.

Shipping: shipped on gel packs

Storage Conditions: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.

Shelf Life: 12 months after date of delivery

Molecular Formula: C9H15N3O10P2 (free acid)

Molecular Weight: 387.17 g/mol (free acid)

CAS#: 178809-71-7

Purity: ≥ 95 % (HPLC)

Form: solution in water

Color: colorless to slightly yellow

Concentration: 10 mM - 11 mM

pH: 7.5 ±0.5

Spectroscopic Properties: λmax 262 nm, ε 10.2 L mmol-1 cm-1 (Tris-HCl pH 7.5)

BIOZ Product Citations:

Selected References:
Kovári et al. (2008) Methylene substitution at the a–b bridging position within the phosphate chain of dUDP profoundly perturbs ligand accommodation into the dUTPase active site. J. Biol. Chem. 71:308.
Barabás et al. (2004) Structural Insights into the Catalytic Mechanism of Phosphate Ester Hydrolysis by dUTPase. J. Biol. Chem. 279 (41):42907.
Persson et al. (1996) Synthesis of 2'-deoxyuridine 5'- (alpha,beta-imido)triphosphate: A substrate analogue and potent inhibitor of dUTPase. Bioorgan. Med. Chem. 4 (4):553.

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